ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2024
Remote Carbon Monoxide Capture via REDCap: Evaluation of an Integrated Mobile Application.
Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Medication Samples and Smoking Cessation Among Adults: A Randomized Clinical Trial.JAMA network open · 2026Trial
- Evidence-based practices are effective in increasing smoke-free home rules among Black women who smoke.Journal of the National Cancer Institute. Monographs · 2025Trial
- Association between IoT-driven dynamic pulmonary function monitoring and quality of life in community-dwelling patients with chronic obstructive pulmonary disease: a 2-year longitudinal study.Frontiers in medicine · 2026Article
- Theory-based strategies to enhance interventions for smoking: Relevance to a digital intervention.Behaviour research and therapy · 2025Review
- Evaluation of a remote biomarker capture system integrated with REDCap: A decentralized randomized trial.Journal of clinical and translational science · 2025Article
- Advancing translational science through trial integrity: REDCap-based approaches to mitigating fraud and bias.Journal of clinical and translational science · 2025Article
- Reintroducing face-to-face support alongside remote support to form a hybrid stop smoking service in England: a formative mixed methods evaluation.BMC public health · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
introductionTo improve the feasibility of remote biochemical verification of smoking status, our team developed "COast," a mobile app integrated with REDCap that allows a research participant to complete self-report research assessments and provide a breath sample via the iCOQuit Smokerlyzer for the purposes of carbon monoxide (CO) testing. The aims of the present study were to examine (1) the validity of remote CO data capture using COast as compared to gold-standard approaches (salivary cotinine, stand-alone CO monitor) and (2) the feasibility of remote CO data capture using COast as applied to both daily and weekly CO collection schedules.
methodsParticipants (N = 143, 59% Female), including recently quit (n = 36) and current (n = 107) smokers, completed a baseline video session to capture validity data, and then were randomized to daily or weekly CO monitoring for a period of 1 month.
resultsBalancing both sensitivity and specificity, optimal cut-points for defining abstinence using the COast system were <4 parts per million (ppm) with salivary cotinine as the referent (Sensitivity = 100%, Specificity = 92.8%) and <8 ppm with the stand-alone CO monitor as the referent (Sensitivity = 100%, Specificity = 88.9%). Compliance across groups with CO monitoring was high with average compliance of 74% for the daily group and 84% for the weekly group. Self-reported feasibility and acceptability of using the system were strong.
conclusionsPairing the iCOQuit with REDCap via the COast app was both valid and feasible among a sample of adults who smoke cigarettes enrolled remotely. This integration may help to improve the rigor of decentralized smoking cessation trials. IMPLICATIONS: With increasing prevalence of decentralized trial designs, innovative methods are needed to remotely capture biomarkers. Methods that leverage existing widely available research data capture platforms may be particularly useful for promoting adoption. The COast app, which integrates a Bluetooth-enabled CO monitor with REDCap, is a fitting, valid, and feasible solution to remotely biochemically verify smoking status.
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