Evidence map›Paper›PMID 37982962›Full record

ArticleProbiotics and antimicrobial proteins2024

Effects of Sub-Minimum Inhibitory Concentrations of Bacteriocin BM173 on Listeria Monocytogenes Biofilm Formation.

Zhu Qiao, Xing Guo, Tao Wang, Jiangmian Wei, Yingying Liu, Yan Ma, Xin Lü

Abstract read
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In one paragraph

Article in Probiotics and antimicrobial proteins, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Zhu QiaoSchool of Biological and Food Processing Engineering, Huanghuai University, Zhumadian, Henan Province 463000, China. qiaozhu2009@163.com.
Xing GuoCollege of Food Science and Technology, Northwest University, Xi'an, Shaanxi, 710069, China.
Tao WangFaculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming, 650500, China.
Jiangmian WeiSchool of Biological and Food Processing Engineering, Huanghuai University, Zhumadian, Henan Province 463000, China.
Yingying LiuSchool of Biological and Food Processing Engineering, Huanghuai University, Zhumadian, Henan Province 463000, China.
Yan MaSchool of Biological and Food Processing Engineering, Huanghuai University, Zhumadian, Henan Province 463000, China.
Xin LüCollege of Food Science and Engineering, Northwest Agricultural and Forestry University, Yangling, Shaanxi Province, 712100, China. xinlu@nwsuaf.edu.cn.
Huanghuai University · CNKunming University of Science and Technology · CNNorth West Agriculture and Forestry University · CNNorthwest University · CN

Funding

Key Scientific Research Project of Colleges and Universities in Henan Province 23A550018Natural Science Foundation of Henan Province, China 232300420217Science and Technology Development Plan Project of Henan province, China 222102110243Science and technology incubation fund of Huanghuai University XKPY-2022005
6 · The paper itself

Abstract

Listeria monocytogenes is a significant foodborne pathogen that can form biofilms on various food processing surfaces, thereby enhancing resistance to disinfectants and exacerbating harm to human health. Previous studies have indicated that bacteriocin BM173 exhibits antibacterial and antibiofilm activities. In the current study, our aim was to assess the inhibitory mode of action of sub-inhibitory concentrations (SICs, 1/32 × MIC and 1/16 × MIC) of BM173 on the biofilm formation L. monocytogenes. Crystal violet staining assay revealed that SICs of BM173 significantly inhibit L. monocytogenes biofilm formation. Furthermore, the results of swimming motility assay, plate count, ruthenium red staining, and scanning electron microscopy (SEM) revealed that SICs of BM173 could effectively reduce the movement, cell adhesion, and exopolysaccharide (EPS) production of L. monocytogenes, thereby inhibiting biofilm formation. Real-time quantitative PCR analyses further demonstrated that SICs of BM173 down-regulated the expression of biofilm-associated genes, including those encoding adhesion, virulence factors, and quorum sensing. Additionally, SICs of BM173 effectively reduced the biofilm formation of L. monocytogenes on the surfaces of three food-grade materials (glass, stainless steel, and silicone) at 4 and 25 °C. These outcomes suggest that BM173 holds great potential for development as a promising food preservative for application in the food industry.

Indexed as

Anti-Bacterial AgentsBacteriocinsBiofilmsListeria monocytogenesBacterial AdhesionFood MicrobiologyMicrobial Sensitivity TestsQuorum SensingAnti-Bacterial AgentsBacteriocinsBacteriocinBiofilmQuorum sensingSub-inhibitory concentrations

Identifiers

PMID37982962
OpenAlexW4388829634

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.