Evidence map›Paper›PMID 37982947›Full record

ArticleEndocrine2024

Thyroid function in pediatric patients with juvenile idiopathic arthritis.

Mariella Valenzise, Federica D'Amico, Eleonora Tripodi, Giuseppina Zirilli, Angela Alibrandi, Romina Gallizzi, Diana Sutera, Giulia Cafarella, Cecilia Lugarà, Malgorzata Gabriela Wasniewska

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Article in Endocrine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mariella ValenziseDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy. mvalenzise@unime.it.
Federica D'AmicoDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.
Eleonora TripodiDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.
Giuseppina ZirilliDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.
Angela AlibrandiDepartment of Economics, University of Messina, Messina, Italy.
Romina GallizziDepartment of Health Sciences, University "Magna Graecia" of Catanzaro, Catanzaro, Italy.
Diana SuteraDepartment of Health Sciences, University "Magna Graecia" of Catanzaro, Catanzaro, Italy.
Giulia CafarellaDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.
Cecilia LugaràDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.
Malgorzata Gabriela WasniewskaDepartment of Human Pathology of Adulthood and Childhood, University of Messina, Messina, Italy.
University of Messina · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeJuvenile Idiopathic Arthritis (JIA) is a chronic inflammatory disease characterized by chronic synovitis, sometimes associated with fever, rash, pericarditis and uveitis. Limited data are available concerning autoimmune diseases associated with JIA in childhood. THE AIMS OF OUR STUDY WERE: (a) evaluating the thyroid function in a group of Italian children affected by JIA; (b) identifying which Autoimmune Thyroid Diseases (ATDs) are related to JIA in this population.

methodsA population of 51 patients with JIA was investigated. Each patient enrolled was evaluated clinically (family history for Autoimmune Diseases (ADs), personal history and physical examination). In the sample were evaluated thyroid function, inflammation's index and anti-thyroid antibodies.

resultsThe 68.6% (35) of our patients had the oligoarticular form, 27.5% (14) had the polyarticular one, 2% (1) had systemic onset and 2% (1) had undifferentiated arthritis. We focused our attention on the differences between the first two forms. We did not find any difference on the gender prevalence (p > 0.05). A higher presence of anti-TPO antibodies was found in the polyarticular form, with a significant difference with the oligoarticular one (p = 0.032). We researched the anti-hTG antibodies (p > 0.05) and ANA for each group (p > 0.05). We found a significant prevalence of family history for ADs in the polyarticular form (p < 0.05).

conclusionOur findings show the necessity to focus on thyroid function in patients with JIA. Although the oligoarticular form is the most frequent, the polyarticular form shows a higher frequency of thyroid function's alteration. This suggests the need for specific attention in polyarticular form.

Indexed as

Arthritis, JuvenileThyroid GlandAdolescentAutoantibodiesChildChild, PreschoolFemaleHumansItalyMaleThyroid Function TestsAutoantibodiesAutoimmune diseasesAutoimmune ThyroiditisAutoimmunityJIAThyroid function

Identifiers

PMID37982947
OpenAlexW4388825899

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.