Evidence map›Paper›PMID 37982622›Full record

ArticleApplied and environmental microbiology2023

Systems-wide analysis of the ROK-family regulatory gene

Chao Li, Mia Urem, Chao Du, Le Zhang, Gilles P van Wezel

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chao LiMolecular Biotechnology, Leiden University, Leiden, the Netherlands.ORCID 0000-0002-8062-4539
Mia UremDepartment of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands.
Chao DuMolecular Biotechnology, Leiden University, Leiden, the Netherlands.ORCID 0000-0003-3447-5293
Le ZhangMolecular Biotechnology, Leiden University, Leiden, the Netherlands.
Gilles P van WezelMolecular Biotechnology, Leiden University, Leiden, the Netherlands.ORCID 0000-0003-0341-1561
Leiden University · NLLeiden University Medical Center · NL

Funding

China Scholarship Council (CSC)EC | H2020 | PRIORITY 'Excellent science' | H2020 European Research Council (ERC) 101055020
6 · The paper itself

Abstract

importanceCentral metabolism plays a key role in the control of growth and antibiotic production in streptomycetes. Specifically, aminosugars act as signaling molecules that affect development and antibiotic production, via metabolic interference with the global repressor DasR. While aminosugar metabolism directly connects to other major metabolic routes such as glycolysis and cell wall synthesis, several important aspects of their metabolism are yet unresolved. Accumulation of

Indexed as

StreptomycesStreptomyces coelicolorAmino SugarsAnti-Bacterial AgentsBacterial ProteinsGene Expression Regulation, BacterialGenes, RegulatorGlucosamineAmino SugarsAnti-Bacterial AgentsBacterial ProteinsGlucosamineaminosugar metabolismcontrol of antibiotic productionROK-family proteinStreptomyces biologysystems biology

Identifiers

PMID37982622
PMCPMC10734537
OpenAlexW4388826058

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.