Evidence map›Paper›PMID 37982580›Full record

ReviewJournal of agricultural and food chemistry2023

Branched-Long-Chain Monomethyl Fatty Acids: Are They Hidden Gems?

Siqing Mao, Ziling Liu, Yuan Tian, Dan Li, Xin Gao, Yanqiong Wen, Tao Peng, Weijun Shen, Dingfu Xiao, Fachun Wan and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of agricultural and food chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Siqing MaoCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Ziling LiuCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Yuan TianCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Dan LiCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Xin GaoCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Yanqiong WenCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Tao PengCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.
Weijun ShenCollege of Animal Science, Hunan Agricultural University, Changsha 410128, China.
Dingfu XiaoCollege of Animal Science, Hunan Agricultural University, Changsha 410128, China.
Fachun WanCollege of Animal Science, Hunan Agricultural University, Changsha 410128, China.
Lei LiuCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, China.ORCID 0000-0002-7009-8264
Hunan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Branched-long-chain monomethyl fatty acids (BLCFA) are consumed daily in significant amounts by humans in all stages of life. BLCFA are absorbed and metabolized in human intestinal epithelial cells and are not only oxidized for energy. Thus far, BLCFA have been revealed to possess versatile beneficial bioactivities, including cytotoxicity to cancer cells, anti-inflammation, lipid-lowering, reducing the risk of metabolic disorders, maintaining normal β cell function and insulin sensitivity, regulation of development, and mitigating cerebral ischemia/reperfusion injury. However, compared to other well-studied dietary fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), BLCFA has received disproportionate attention despite their potential importance. Here we outlined the major food sources, estimated intake, absorption, and metabolism in human cells, and bioactive properties of BLCFA with a focus on the bioactive mechanisms to advocate for an increased commitment to BLCFA investigations. Humans were estimated to absorb 6-5000 mg of dietary BLCFA daily from fetus to adult. Notably,

Indexed as

Fatty Acids, Omega-3Reperfusion InjuryAdultAnimalsDietDocosahexaenoic AcidsEicosapentaenoic AcidFatty AcidsHumansMaleRatsDocosahexaenoic AcidsEicosapentaenoic AcidFatty AcidsFatty Acids, Omega-3biological activitybranched-chain fatty acidsdietary fatsmechanism

Identifiers

PMID37982580
PMCPMC10705331
OpenAlexW4388826091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.