Evidence map›Paper›PMID 37982203›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2023

Novel

Hesham Haffez, Nosaiba A Elsayed, Marwa F Ahmed, Samar S Fatahala, Eman F Khaleel, Rehab Mustafa Badi, Eslam B Elkaeed, Mahmoud A El Hassab, Sherif F Hammad, Wagdy M Eldehna and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 5 countries.

Hesham HaffezBiochemistry and Molecular Biology Department, Faculty of Pharmacy, Helwan University, Cairo, Ain Helwan, Egypt.ORCID 0000-0002-9924-2063
Nosaiba A ElsayedDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Ain Helwan, Egypt.
Marwa F AhmedDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Ain Helwan, Egypt.
Samar S FatahalaPharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
Eman F KhaleelDepartment of Medical Physiology, College of Medicine, King Khalid University, Asir, Saudi Arabia.
Rehab Mustafa BadiDepartment of Medical Physiology, College of Medicine, King Khalid University, Asir, Saudi Arabia.
Eslam B ElkaeedDepartment of Pharmaceutical Sciences, College of Pharmacy, AlMaarefa University, Riyadh, Saudi Arabia.
Mahmoud A El HassabDepartment of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Egypt.
Sherif F HammadDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Ain Helwan, Egypt.
Wagdy M EldehnaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.ORCID 0000-0001-6996-4017
Nicolas MasurierInstitut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université de Montpellier, ENSCM, Montpellier, France.ORCID 0000-0001-9169-8149
Radwan El-HaggarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Ain Helwan, Egypt.ORCID 0000-0002-3878-9890
Helwan University · EGKing Khalid University · SAAlfaisal University · SAÉcole Nationale Supérieure de Chimie de Montpellier · FREgypt-Japan University of Science and Technology · EGKafrelsheikh University · EGKing Salman International University

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significant advancements have been made in the domain of targeted anticancer therapy for the management of malignancies in recent times. VEGFR-2 is characterised by its pivotal involvement in angiogenesis and subsequent mechanisms that promote tumour cells survival. Herein, novel

Indexed as

ChalconeChalconesAniline CompoundsMolecular Docking SimulationMolecular Dynamics SimulationVascular Endothelial Growth Factor Receptor-2anilineAniline CompoundsChalconeChalconesVascular Endothelial Growth Factor Receptor-2anticancer agentsapoptosis inductionmolecular dockingVEGFR-2

Identifiers

PMID37982203
PMCPMC11003488
OpenAlexW4388828962

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.