ArticleJournal of mood and anxiety disorders2023
Characterizing positive and negative valence systems function in adolescent depression: An RDoC-informed approach integrating multiple neural measures.
Article in Journal of mood and anxiety disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Neural reactivity to infant faces and trait mindfulness as prospective predictors of postpartum depressive symptoms.Cognitive, affective & behavioral neuroscience · 2026Article
- Everyday stress-induced neurobehavioral dysregulation: therapeutic targets for management with Neurexan.Frontiers in psychiatry · 2025Review
- Depressive symptoms and suicidal ideation in sexual minority adolescents: An examination of social reward responsiveness and support as moderators.Journal of mood and anxiety disorders · 2024Article
- Reduced reward responsiveness and depression vulnerability: Consideration of social contexts and implications for intervention.Psychophysiology · 2024Review
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Authors and funding
8 authors.
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Abstract
Depression is a prevalent, debilitating, and costly disorder that often manifests in adolescence. There is an urgent need to understand core pathophysiological processes for depression to inform more targeted intervention efforts. The Research Domain Criteria (RDoC) Positive Valence Systems (PVS) and Negative Valence Systems (NVS) have both been implicated in depression symptomatology and vulnerability; however, the nature of NVS alterations is unclear across studies, and associations between single neural measures and symptoms are often small in magnitude and inconsistent. The present study advances characterization of depression in adolescence via an innovative data-driven approach to identifying subgroups of PVS and NVS function by integrating multiple neural measures (assessed by electroencephalogram [EEG]) relevant to depression in adolescents oversampled for clinical depression and depression risk based on maternal history (
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Registered trials
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