Evidence map›Paper›PMID 37982044›Full record

ArticleJournal of statistical theory and applications : JSTA2023

Continuity corrected Wilson interval for the difference of two independent proportions.

Guogen Shan, XiangYang Lou, Samuel S Wu

Abstract read
In one paragraph

Article in Journal of statistical theory and applications : JSTA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Guogen ShanDepartment of Biostatistics, University of Florida, Gainesville, FL 32610.
XiangYang LouDepartment of Biostatistics, University of Florida, Gainesville, FL 32610.
Samuel S WuDepartment of Biostatistics, University of Florida, Gainesville, FL 32610.

Funding

Alzheimer's Disease: New Trial Designs for Emerging ChallengesR01AG070849 · NIA · UNIVERSITY OF NEVADA LAS VEGAS · PI SHAN, GUOGEN · 2021 to 2025
$1.5M
Adaptive randomized designs for cancer clinical trials by using integer algorithms and exact Monte Carlo methodsR03CA248006 · NCI · UNIVERSITY OF FLORIDA · PI SHAN, GUOGEN · 2021 to 2022
$153k
NCI NIH HHS R03 CA248006NIA NIH HHS R01 AG070849
6 · The paper itself

Abstract

Confidence interval for the difference of two proportions has been studied for decades. Many methods were developed to improve the approximation of the limiting distribution of test statistics, such as the profile likelihood method, the score method, and the Wilson method. For the Wilson interval developed by Beal (1987), the approximation of the Z test statistic to the standard normal distribution may be further improved by utilizing the continuity correction, in the observation of anti-conservative intervals from the Wilson interval. We theoretically prove that the Wilson interval is nested in the continuity corrected Wilson interval under mild conditions. We compare the continuity corrected Wilson interval with the commonly used methods with regards to coverage probability, interval width, and mean squared error of coverage probability. The proposed interval has good performance in many configurations. An example from a Phase II cancer trial is used to illustrate the application of these methods.

Indexed as

Confidence intervalContinuity correctionIndependent proportionsRisk differenceWilson interval

Identifiers

PMID37982044
PMCPMC10655805

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.