Evidence map›Paper›PMID 37981977›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2023

A Preclinical Positron Emission Tomography (PET) and Electron-Paramagnetic-Resonance-Imaging (EPRI) Hybrid System: PET Detector Module.

Heejong Kim, Yuexuan Hua, Boris Epel, Subramanian Sundramoorthy, Howard Halpern, Chin-Tu Chen, Chien-Min Kao

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Heejong KimDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.
Yuexuan HuaRaycan Technology Co., Ltd., Suzhou, Jiangsu, China.
Boris EpelDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA.
Subramanian SundramoorthyDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA.
Howard HalpernDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA.
Chin-Tu ChenDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.
Chien-Min KaoDepartment of Radiology, University of Chicago, Chicago, Illinois, USA.

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI CHIEN-MIN KAO · 1985 to 2026
$122.1M
Radiation Biology of EPR Oxygen ImagesR01CA098575 · NCI · UNIVERSITY OF CHICAGO · PI HALPERN, HOWARD J · 2003 to 2022
$4.5M
Improved Radiation Therapy of Hypoxic Tumor Regions by Integrated PET, EPR, and MR Imaging - Resubmission 01 - Revision - 1R01CA236385 · NCI · UNIVERSITY OF CHICAGO · PI CHEN, CHIN-TU, HALPERN, HOWARD J · 2020 to 2024
$3.3M
A preclinical integrated PET/EPR imaging system-Rev3R01EB029948 · NIBIB · UNIVERSITY OF CHICAGO · PI EPEL, BORIS, KAO, CHIEN-MIN · 2020 to 2023
$1.7M
Tileable DOI/TOF capable PET detector unit with flexible sampling/digital architecture for data acquisition?R03EB027343 · NIBIB · UNIVERSITY OF CHICAGO · PI KAO, CHIEN-MIN · 2018 to 2019
$162k
NCI NIH HHS P30 CA014599NCI NIH HHS R01 CA098575NCI NIH HHS R01 CA236385NIBIB NIH HHS R01 EB029948NIBIB NIH HHS R03 EB027343
6 · The paper itself

Abstract

We report the design and experimental validation of a compact positron emission tomography (PET) detector module (DM) intended for building a preclinical PET and electron-paramagnetic-resonance-imaging hybrid system that supports sub-millimeter image resolution and high-sensitivity, whole-body animal imaging. The DM is eight detector units (DU) in a row. Each DU contains 12×12 lutetium-yttrium oxyorthosilicate (LYSO) crystals having a 1.05 mm pitch read by 4×4 silicon photomultipliers (SiPM) having a 3.2 mm pitch. A small-footprint, highly-multiplexing readout employing only passive electronics is devised to produce six outputs for the DM, including two outputs derived from SiPM cathodes for determining event time and active DU and four outputs derived from SiPM anodes for determining energy and active crystal. Presently, we have developed two DMs that are 1.28×10.24 cm

Indexed as

EPRImulti-modalityPETresistive networkstripline

Identifiers

PMID37981977
PMCPMC10655702

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.