Evidence map›Paper›PMID 37981946›Full record

ArticleNature computational science2022

A laboratory and simulation platform to integrate individual life history traits and population dynamics.

Andrea Scharf, Josh Mitteldorf, Brinda Armstead, Daniel Schneider, He Jin, Zuzana Kocsisova, Chieh-Hsiang Tan, Francesca Sanchez, Brian Brady, Natasha Ram and 3 more

Abstract read
In one paragraph

Article in Nature computational science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andrea ScharfDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Josh MitteldorfDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Brinda ArmsteadDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Daniel SchneiderDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
He JinDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Zuzana KocsisovaDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Chieh-Hsiang TanDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Francesca SanchezDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Brian BradyDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Natasha RamDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Gabriel B DiAntonioDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.
Andrea M WilsonCenter for the Study of Collaboration, 9378 Olive Blvd., Ste 122, Saint Louis, MO 63132.
Kerry KornfeldDepartment of Developmental Biology, Washington University School of Medicine, 660 S Euclid Ave, St. Louis, MO 63110.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
IDENTIFICATION OF DRUGS THAT DELAY AGINGR01AG026561 · NIA · WASHINGTON UNIVERSITY · PI KORNFELD, KERRY · 2006 to 2017
$3.3M
DISCOVER DETERMINANTS OF INDIVIDUAL LIFESPAN AND HEALTHR01AG057748 · NIA · WASHINGTON UNIVERSITY · PI KORNFELD, KERRY · 2019 to 2023
$2.1M
NIA NIH HHS R01 AG026561NIA NIH HHS R01 AG057748NIH HHS P40 OD010440
6 · The paper itself

Abstract

Understanding populations is important because they are a fundamental level of biological organization. Individual traits such as aging and lifespan interact in complex ways to determine birth and death and thereby influence population dynamics. However, we lack a deep understanding of the relationships between individual traits and population dynamics. To address this challenge, we established a laboratory population using the model organism

Identifiers

PMID37981946
PMCPMC10655596

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.