ArticleInternational journal of mass spectrometry2024
Triboelectric Nanogenerator-Coated Blade Spray Mass Spectrometry for Volume-Limited Drug Analysis.
Article in International journal of mass spectrometry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Advancements in Ambient Ionisation Mass Spectrometry in 2024: An Annual Review.Analytical science advances · 2025Review
- Triboelectric Nanogenerators for the Masses: A Low-Cost Do-It-Yourself Pulsed Ion Source for Sample-Limited Applications.Journal of the American Society for Mass Spectrometry · 2024Article
- Rapid, Sensitive, and Versatile: A 5-Year Perspective on Applications of Ambient Ionization Mass Spectrometry in Bioanalytical Science.Mass spectrometry reviewsReview
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Authors and funding
2 authors.
Funding
Abstract
The demand for analytical tools for the analysis of low-concentration volume-limited samples has driven researchers to explore new analytical approaches. Mass spectrometry excels at trace analysis due to its high sensitivity and specificity, whereas ambient methods simplify, or completely eliminate sample preparation. Herein, we report a triboelectric nanogenerator-coated blade spray ambient mass spectrometry (TENG-CBS MS) method for the extraction, elution, and ionization of volume-limited, low-concentration small molecule drug samples with minimum sample preparation. Using a TENG device as the CBS power supply, we show it is possible to extract and analyze drug samples in a pulsed fashion at sub-nanogram to picogram levels with good stability and reproducibility. A wide range of analytes polarities were tested. Results indicated this method could also be useful for the analysis of low-level analytes in precious, volume limited samples in a simple single step.
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Registered trials
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