Evidence map›Paper›PMID 37981566›Full record

ArticleBJPsych open2023

Suicidal ideation across depressive episodes: 9-year longitudinal cohort study.

Liia M M Kivelä, Niki Antypa, Eiko I Fried, Robert Schoevers, Albert M van Hemert, Brenda W J H Penninx, A J Willem van der Does

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Article in BJPsych open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Liia M M KiveläDepartment of Clinical Psychology, Institute of Psychology, Leiden University, Leiden, The Netherlands.ORCID https://orcid.org/0000-0003-2051-5039
Niki AntypaDepartment of Clinical Psychology, Institute of Psychology, Leiden University, Leiden, The Netherlands.
Eiko I FriedDepartment of Clinical Psychology, Institute of Psychology, Leiden University, Leiden, The Netherlands.
Robert SchoeversUniversity Center for Psychiatry, University Medical Center Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0003-0760-9866
Albert M van HemertDepartment of Psychiatry, Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Brenda W J H PenninxDepartment of Psychiatry, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands.
A J Willem van der DoesDepartment of Clinical Psychology, Institute of Psychology, Leiden University, Leiden, The Netherlands; and Leiden University Treatment Center (LUBEC), Leiden, The Netherlands.

Funding

ZonMw 10-000-1002
6 · The paper itself

Abstract

backgroundDepression is a highly recurrent disorder, with more than 50% of those affected experiencing a subsequent episode. Although there is relatively little stability in symptoms across episodes, some evidence indicates that suicidal ideation may be an exception. However, these findings warrant replication, especially over longer periods and across multiple episodes.

aimsTo assess the relative stability of suicidal ideation in comparison with other non-core depressive symptoms across episodes.

methodWe examined 490 individuals with current major depressive disorder (MDD) at baseline and at least one subsequent episode during 9-year follow-up within the Netherlands Study of Depression and Anxiety (NESDA). The Inventory of Depressive Symptomatology (IDS) was used to assess DSM-5 non-core MDD symptoms (fatigue, appetite/weight change, sleep disturbance, psychomotor disturbance, concentration difficulties, worthlessness/guilt, suicidal ideation) at baseline and 2-, 4-, 6- and 9-year follow-up. We examined consistency in symptom presentation (i.e. whether the symptom met the diagnostic threshold, based on a binary categorisation of the IDS) using kappa (κ) and percentage agreement, and stability in symptom severity using Spearman correlation, based on the continuous IDS scores.

resultsOut of all non-core depressive symptoms, insomnia appeared the most stable across episodes (

conclusionsSuicidal ideation is moderately stable in recurrent depression over 9 years. Contrary to prior reports, however, it does not exhibit substantially more stability than most other non-core symptoms of depression.

Indexed as

Depressioninsomniarecurrencesleep disturbancesuicidal ideation

Identifiers

PMID37981566
PMCPMC10755669

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