Guillain-Barré Syndrome Mimicking Lumbar Spinal Stenosis with Segmental Weakness in L5-S1 Myotomes.

Yuichi Hamada, Keiichi Hokkoku, Yuki Hatanaka, Ayumi Uchibori, Kenichi Kaida, Masahiro Sonoo, Shunsuke Kobayashi

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In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Yuichi HamadaDepartment of Neurology, Teikyo University School of Medicine, Japan.

Keiichi HokkokuDepartment of Neurology, Teikyo University School of Medicine, Japan.

Yuki HatanakaDepartment of Neurology, Teikyo University School of Medicine, Japan.

Ayumi UchiboriDepartment of Neurology, Kyorin University School of Medicine, Japan.

Kenichi KaidaDepartment of Neurology, Saitama Medical Center, Saitama Medical University, Japan.

Masahiro SonooDepartment of Neurology, Teikyo University School of Medicine, Japan.

Shunsuke KobayashiDepartment of Neurology, Teikyo University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report two cases of Guillain-Barré syndrome (GBS) mimicking lumbar spinal stenosis (LSS). Both cases were initially diagnosed as LSS based on prominent segmental weakness in the L5 and S1 myotomes and coexisting LSS on magnetic resonance imaging. However, neurological and electrophysiological examinations revealed abnormalities that extended to the upper extremities, although slight, prompting us to suspect GBS. Subsequently, serum antiganglioside antibodies and remarkable responsiveness to intravenous immunoglobulin therapy confirmed GBS. We suspect that the focal blood-nerve barrier disruption due to preexisting LSS might have contributed to the segmental weakness in this atypical GBS case.

Indexed as

Guillain-Barre SyndromeLumbar VertebraeMuscle WeaknessSpinal StenosisDiagnosis, DifferentialHumansImmunoglobulins, IntravenousMagnetic Resonance ImagingImmunoglobulins, Intravenousblood-nerve barrierGuillain-Barré syndromelumbar spinal stenosisparaparetic GBS

Identifiers

PMID37981299

DOI10.2169/internalmedicine.2875-23

PMCPMC11309858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.