Evidence map›Paper›PMID 37980803›Full record

ReviewCurrent opinion in neurobiology2023

Dendrites and efficiency: Optimizing performance and resource utilization.

Roman Makarov, Michalis Pagkalos, Panayiota Poirazi

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current opinion in neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Roman MakarovInstitute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology Hellas (FORTH), Heraklion, 70013, Greece; Department of Biology, University of Crete, Heraklion, 70013, Greece. Electronic address: https://twitter.com/_RomanMakarov.
Michalis PagkalosInstitute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology Hellas (FORTH), Heraklion, 70013, Greece; Department of Biology, University of Crete, Heraklion, 70013, Greece. Electronic address: https://twitter.com/MPagkalos.
Panayiota PoiraziInstitute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology Hellas (FORTH), Heraklion, 70013, Greece. Electronic address: poirazi@imbb.forth.gr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain is a highly efficient system that has evolved to optimize performance under limited resources. In this review, we highlight recent theoretical and experimental studies that support the view that dendrites make information processing and storage in the brain more efficient. This is achieved through the dynamic modulation of integration versus segregation of inputs and activity within a neuron. We argue that under conditions of limited energy and space, dendrites help biological networks to implement complex functions such as processing natural stimuli on behavioral timescales, performing the inference process on those stimuli in a context-specific manner, and storing the information in overlapping populations of neurons. A global picture starts to emerge, in which dendrites help the brain achieve efficiency through a combination of optimization strategies that balance the tradeoff between performance and resource utilization.

Indexed as

DendritesNeuronsBrainCognition

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.