Evidence map›Paper›PMID 37980766›Full record

ArticleGynecologic oncology2023

Cervical cancer treatment update: A Society of Gynecologic Oncology clinical practice statement.

Eugenia Girda, Leslie M Randall, Fumiko Chino, Bradley J Monk, John H Farley, Roisin E O'Cearbhaill

Open access · hybridAbstract read
In one paragraph

Article in Gynecologic oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
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  9. Thieno[2,3-International journal of molecular sciences · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Contemporary Review of Adenocarcinoma of the Cervix.Current treatment options in oncology · 2024
    Review
  15. How to optimize and evaluate diversity in gynecologic cancer clinical trials: statements from the GCIG Barcelona Meeting.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Eugenia GirdaRutgers Cancer Institute of New Jersey, New Brunswick, NJ, United States of America.
Leslie M RandallDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology and Massey Cancer Center, Virginia Commonwealth University Health, Richmond, VA, United States of America.
Fumiko ChinoDepartment of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America.
Bradley J MonkArizona Oncology (US Oncology Network), University of Arizona, Creighton University, Phoenix, AZ, United States of America.
John H FarleyDepartment of Obstetrics and Gynecology, St Joseph's Hospital and Medical Center, Phoenix, AZ, United States of America.
Roisin E O'CearbhaillDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, United States of America; Department of Medicine, Weill Cornell Medical College, New York, NY, United States of America. Electronic address: ocearbhr@mskcc.org.
Arizona Oncology · USCornell University · USMemorial Sloan Kettering Cancer Center · USRutgers Cancer Institute of New JerseySt. Joseph's Hospital and Medical Center · USVirginia Commonwealth University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Cervical cancer is the most commonly diagnosed gynecologic cancer worldwide. Although the incidence has declined with increased screening and higher uptake of human papillomavirus (HPV) vaccination in high-income countries, this disease remains the second highest cause of cancer mortality among women in low- and middle-income countries. In this clinical practice statement, we describe therapies for cervical cancer by treatment setting, as well as quality of life, financial toxicity, and disparities associated with this disease. In addition to chemotherapy and radiation, therapeutic strategies for cervical cancer include immune checkpoint blockade, antiangiogenics, and antibody-drug conjugates. Optimal treatment for recurrent cervical cancer remains an area of unmet need, necessitating further exploration of rational and innovative treatment approaches, including cell and immune-based therapies. Importantly, development of effective therapies for cervical cancer must incorporate strategies to ensure universal equitable access to HPV vaccination, screening, and treatment. Important consequences of the disease and treatment that impact quality of life must also be addressed. Patients with cervical cancer are at increased risk for financial toxicity, which can lead to downstream detrimental effects on physical, financial, and career outcomes. Underrepresentation of racial and ethnic minorities in gynecologic oncology clinical trials highlights the urgent need for collaborative and focused initiatives to bridge the significant divide and alleviate inequalities in the prevention and treatment of cervical cancer.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsCervix UteriFemaleHumansNeoplasm Recurrence, LocalQuality of LifePapillomavirus VaccinesCervical cancerSociety of Gynecologic OncologyTreatment

Identifiers

PMID37980766
PMCPMC11001261
OpenAlexW4388750485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.