Evidence map›Paper›PMID 37980575›Full record

ReviewRestorative neurology and neuroscience2023

Targeted neurorehabilitation strategies in post-stroke aphasia.

Priyanka Shah-Basak, Olga Boukrina, Xin Ran Li, Fatima Jebahi, Aneta Kielar

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Restorative neurology and neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06974279 (Precision Neuromodulation in Post-Stroke Aphasia Using TMS), which is not on this map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06974279 narecruitingnot on this mapstarted 2025, after this paper: background citation

Precision Neuromodulation in Post-Stroke Aphasia Using TMS

TypeinterventionalSponsorMedical College of WisconsinRan2025 to 2036Enrolled50ConditionsAphasia, Stroke, LanguageArmsPrecision TMS with SFA, Control TMS with SFA
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Observational
  6. Advances in Neuromodulation Techniques for Aphasia Rehabilitation: A Comprehensive Review.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Priyanka Shah-BasakDepartment of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.
Olga BoukrinaKessler Foundation, Center for Stroke Rehabilitation Research, West Orange, NJ, USA.
Xin Ran LiSchool of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Fatima JebahiDepartment of Speech, Languageand Hearing Sciences, University of Arizona, Tucson, AZ, USA.
Aneta KielarDepartment of Speech, Languageand Hearing Sciences, University of Arizona, Tucson, AZ, USA.
Medical College of Wisconsin · USUniversity of Arizona · USKessler Foundation · US

Funding

Rehabilitation of Reading Deficits in Subacute Stroke using fMRI Neurofeedback and Motor ImageryK01DC019178 · NIDCD · KESSLER FOUNDATION, INC. · PI BOUKRINA, OLGA · 2021 to 2025
$657k
NIDCD NIH HHS K01 DC019178
6 · The paper itself

Abstract

backgroundAphasia is a debilitating language impairment, affecting millions of people worldwide. About 40% of stroke survivors develop chronic aphasia, resulting in life-long disability.

objectiveThis review examines extrinsic and intrinsic neuromodulation techniques, aimed at enhancing the effects of speech and language therapies in stroke survivors with aphasia.

methodsWe discuss the available evidence supporting the use of transcranial direct current stimulation (tDCS), repetitive transcranial magnetic stimulation, and functional MRI (fMRI) real-time neurofeedback in aphasia rehabilitation.

resultsThis review systematically evaluates studies focusing on efficacy and implementation of specialized methods for post-treatment outcome optimization and transfer to functional skills. It considers stimulation target determination and various targeting approaches. The translation of neuromodulation interventions to clinical practice is explored, emphasizing generalization and functional communication. The review also covers real-time fMRI neurofeedback, discussing current evidence for efficacy and essential implementation parameters. Finally, we address future directions for neuromodulation research in aphasia.

conclusionsThis comprehensive review aims to serve as a resource for a broad audience of researchers and clinicians interested in incorporating neuromodulation for advancing aphasia care.

Indexed as

AphasiaNeurological RehabilitationStrokeTranscranial Direct Current StimulationHumansTranscranial Magnetic StimulationaphasiafMRIgeneralizationneuromodulationreal-time neurofeedbackrTMSStroketDCS

Identifiers

PMID37980575
PMCPMC10741339
OpenAlexW4388775498

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.