Evidence map›Paper›PMID 37980564›Full record

ArticleCell reports2023

Engineered bacteria titrate hydrogen sulfide and induce concentration-dependent effects on the host in a gut microphysiological system.

Justin A Hayes, Anna W Lunger, Aayushi S Sharma, Matthew T Fernez, Rebecca L Carrier, Abigail N Koppes, Ryan Koppes, Benjamin M Woolston

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Metabolic engineering ofbioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Justin A HayesDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Anna W LungerDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Aayushi S SharmaDepartment of Mechanical and Industrial Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA; Department of Bioengineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Matthew T FernezDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Rebecca L CarrierDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA; Department of Bioengineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA; Department of Biology, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Abigail N KoppesDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA; Department of Bioengineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA.
Ryan KoppesDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA. Electronic address: r.koppes@northeastern.edu.
Benjamin M WoolstonDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, MA 02115, USA. Electronic address: b.woolston@northeastern.edu.
Northeastern University · US

Funding

Impact of Lipids on Compound Absorption: Mechanistic Studies and ModelingR01GM098117 · NIGMS · NORTHEASTERN UNIVERSITY · PI CARRIER, REBECCA L · 2012 to 2021
$3.3M
Engineering multifaceted 3D human organ platforms for toxicity testingR35GM142741 · NIGMS · NORTHEASTERN UNIVERSITY · PI KOPPES, RYAN ALAN · 2021 to 2025
$2.0M
Engineered Probiotics for Closed-Loop Control of Disease-Associated Gut Metabolites in Gut-On-Chip ModelsR21EB033892 · NIBIB · NORTHEASTERN UNIVERSITY · PI WOOLSTON, BENJAMIN MICHAEL · 2022 to 2024
$636k
NIBIB NIH HHS R21 EB033892NIGMS NIH HHS R01 GM098117NIGMS NIH HHS R35 GM142741
6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

Gastrointestinal MicrobiomeHydrogen SulfideAnimalsBacteriaEscherichia coliHost Microbial InteractionsHumansMicrophysiological SystemsHydrogen SulfidebioengineeringCP: Microbiologygut metabolomegut microbiomegut microphysiological systemgut on a chiphost-microbe interactionshydrogen sulfideinflammatory bowel diseasemetabolic engineeringsynthetic biology

Identifiers

PMID37980564
PMCPMC10791167
OpenAlexW4388789614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.