Evidence map›Paper›PMID 37979582›Full record

ArticleCell2023

ABLs and TMKs are co-receptors for extracellular auxin.

Yongqiang Yu, Wenxin Tang, Wenwei Lin, Wei Li, Xiang Zhou, Ying Li, Rong Chen, Rui Zheng, Guochen Qin, Wenhan Cao and 10 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
34.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 89 citations in OpenAlex.

  1. Review
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  5. Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026
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  8. Plant cell surface receptors.The Plant journal : for cell and molecular biology · 2026
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Aux/IAAs: specificity and redundancy.Plant signaling & behavior · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Mechanisms of auxin action in plant growth and development.Nature reviews. Molecular cell biology · 2025
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 2 countries.

Yongqiang YuHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China; Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, P.R. China.
Wenxin TangHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Wenwei LinHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Wei LiHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China; College of Life Sciences, Nanjing Agricultural University, Nanjing, Jiangsu 210095, P.R. China.
Xiang ZhouHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China; Faculty of Synthetic Biology, Shenzhen Institute of Advanced Technology, Shenzhen, Guangdong 518055, P.R. China; Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, P.R. China.
Ying LiHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Rong ChenCenter for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, P.R. China.
Rui ZhengCenter for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, P.R. China.
Guochen QinCenter for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, P.R. China; Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences at Weifang, Weifang, Shandong 261000, P.R. China.
Wenhan CaoSchool of Life Sciences, Centre for Cell and Developmental Biology and State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, P.R. China.
Patricio Pérez-HenríquezInstitute of Integrative Genome Biology, and Department of Botany and Plant Sciences, University of California-Riverside, Riverside, CA 92507, USA.
Rongfeng HuangHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Jun MaHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Qiqi QiuCollege of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Ziwei XuHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Ailing ZouHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Juncheng LinHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China.
Liwen JiangSchool of Life Sciences, Centre for Cell and Developmental Biology and State Key Laboratory of Agrobiotechnology, The Chinese University of Hong Kong, Hong Kong, P.R. China.
Tongda XuHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China; Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, P.R. China. Electronic address: tdxu@sibs.ac.cn.
Zhenbiao YangHaixia Institute of Science and Technology, School of Future Technology, and College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P.R. China; Faculty of Synthetic Biology, Shenzhen Institute of Advanced Technology, Shenzhen, Guangdong 518055, P.R. China; Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong 518055, P.R. China; Institute of Integrative Genome Biology, and Department of Botany and Plant Sciences, University of California-Riverside, Riverside, CA 92507, USA. Electronic address: yang@ucr.edu.
Fujian Agriculture and Forestry University · CNChinese Academy of Sciences · CNChinese University of Hong Kong · CNCenter for Excellence in Molecular Plant Sciences · CNNanjing Agricultural University · CNShenzhen Institutes of Advanced Technology · CNUniversity of California, Riverside · US

Funding

Request for An Integrated Confocal-Atomic Force Microscopy SystemR01GM100130 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI CUI, YONGTAO · 2012 to 2020
$1.9M
NIGMS NIH HHS R01 GM100130
6 · The paper itself

Abstract

Extracellular perception of auxin, an essential phytohormone in plants, has been debated for decades. Auxin-binding protein 1 (ABP1) physically interacts with quintessential transmembrane kinases (TMKs) and was proposed to act as an extracellular auxin receptor, but its role was disputed because abp1 knockout mutants lack obvious morphological phenotypes. Here, we identified two new auxin-binding proteins, ABL1 and ABL2, that are localized to the apoplast and directly interact with the extracellular domain of TMKs in an auxin-dependent manner. Furthermore, functionally redundant ABL1 and ABL2 genetically interact with TMKs and exhibit functions that overlap with those of ABP1 as well as being independent of ABP1. Importantly, the extracellular domain of TMK1 itself binds auxin and synergizes with either ABP1 or ABL1 in auxin binding. Thus, our findings discovered auxin receptors ABL1 and ABL2 having functions overlapping with but distinct from ABP1 and acting together with TMKs as co-receptors for extracellular auxin.

Indexed as

ArabidopsisIndoleacetic AcidsPlant Growth RegulatorsArabidopsis ProteinsPlant ProteinsReceptors, Cell SurfaceArabidopsis Proteinsauxin-binding protein 1auxin receptor, plantIndoleacetic AcidsPlant Growth RegulatorsPlant ProteinsReceptors, Cell SurfaceABL1ABL2ABP1ABP1-like proteinsauxinTMKstransmembrane kinases

Identifiers

PMID37979582
PMCPMC10827329
OpenAlexW4388759124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.