Evidence map›Paper›PMID 37979026›Full record

ArticleBulletin of experimental biology and medicine2023

Phytocorrection of Age-Related Changes in the Composition of Blood Plasma, Lymph, and Interstitial Fluid.

G A Demchenko, B A Nurmakhanova, S N Abdreshov, L U Koibasova, G S Zhunussova, S K Imankulova

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

G A DemchenkoInstitute of Genetics and Physiology, the Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan, Alma-Ata, Republic of Kazakhstan. georgiidemchenko@mail.ru.
B A NurmakhanovaInstitute of Genetics and Physiology, the Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan, Alma-Ata, Republic of Kazakhstan.
S N AbdreshovInstitute of Genetics and Physiology, the Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan, Alma-Ata, Republic of Kazakhstan.
L U KoibasovaInstitute of Genetics and Physiology, the Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan, Alma-Ata, Republic of Kazakhstan.
G S ZhunussovaInstitute of Genetics and Physiology, the Science Committee of the Ministry of Education and Science of the Republic of Kazakhstan, Alma-Ata, Republic of Kazakhstan.
S K ImankulovaAbai Kazakh National Pedagogical University, Alma-Ata, Republic of Kazakhstan.
Ministry of Education and Science of the Republic of Kazakhstan · KZAbai Kazakh National Pedagogical University · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the effect of a new complex phytocomposition on age-related changes in the composition of biological fluids (blood, lymph, and interstitial fluid) in old (22-24-month-old) white Sprague-Dawley rats. A 3-month course of phytocomposition induced an increase in the volumes of interstitial fluid (IF) and plasma and stimulated lymph outflow and diuresis. In the blood and lymph, the clotting time increased, while the viscosity and all lipid indicators decreased. The phytocomposition increased the number of erythrocytes and leukocytes, the levels of immunoglobulins (except IgG) and lymphocyte subpopulations, which contributed to correction and improvement of the immune properties of the blood and lymph. Increased hydration of the tissues of the body and strengthening of the anti-atherogenic and immune properties of the lymph and blood led to recovery of the drainage and detoxification function of the lymphatic system. Due to the presence of bioflavonoids, microelements, and vitamins, the new complex phytocomposition produces a lymphotropic effect by changing the composition of the blood, lymph, and IF and stimulates fluid transport from IF into the vascular bed, thereby promoting natural lymph detoxification and increasing the immune properties of the blood and lymph.

Indexed as

Extracellular FluidLymphAnimalsLymphatic SystemPlasmaRatsRats, Sprague-Dawleybloodinterstitial fluidlymphphytocomposition

Identifiers

PMID37979026
OpenAlexW4388796799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.