Evidence map›Paper›PMID 37978195›Full record

ArticleNature communications2023

TOF

Naomi Hoenisch Gravel, Annika Nelde, Jens Bauer, Lena Mühlenbruch, Sarah M Schroeder, Marian C Neidert, Jonas Scheid, Steffen Lemke, Marissa L Dubbelaar, Marcel Wacker and 12 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 44 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Molecular origin, discovery, validation and application of neoantigens.Asian journal of pharmaceutical sciences · 2026
    Review
  9. Article
  10. Benchmarking Software for DDA-PASEF Immunopeptidomics.Molecular & cellular proteomics : MCP · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Immunoproteomics: The Evolution from Classical Methods to Emerging Techniques.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 2 countries.

Naomi Hoenisch GravelDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0001-9465-0175
Annika NeldeDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0001-8504-8481
Jens BauerDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0003-3731-2385
Lena MühlenbruchDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.
Sarah M SchroederDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0002-4271-1498
Marian C NeidertNeuroscience Center Zürich (ZNZ), University of Zürich and ETH Zürich, Zürich, Switzerland.
Jonas ScheidDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0002-5923-1343
Steffen LemkeDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.
Marissa L DubbelaarDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0002-4930-1467
Marcel WackerDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0002-8185-140X
Anna DenglerDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany.
Reinhild KleinDepartment of Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0002-6111-3901
Paul-Stefan MauzDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Tübingen, Tübingen, Germany.
Hubert LöwenheimDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Tübingen, Tübingen, Germany.
Mathias Hauri-HohlPediatric Stem Cell Transplantation, University Children's Hospital Zürich, Zürich, Switzerland.
Roland MartinNeuroimmunology and MS Research, Neurology Clinic, University and University Hospital Zürich, Zürich, Switzerland.ORCID 0000-0002-0982-1329
Jörg HennenlotterDepartment of Urology, University Hospital Tübingen, Tübingen, Germany.ORCID 0000-0003-3827-6996
Arnulf StenzlDepartment of Urology, University Hospital Tübingen, Tübingen, Germany.
Jonas S HeitmannCluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tübingen, Tübingen, Germany.ORCID 0000-0002-7305-8620
Helmut R SalihCluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tübingen, Tübingen, Germany.ORCID 0000-0002-6719-1847
Hans-Georg RammenseeInstitute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.
Juliane S WalzDepartment of Peptide-based Immunotherapy, University and University Hospital Tübingen, Tübingen, Germany. juliane.walz@med.uni-tuebingen.de.ORCID 0000-0001-6404-7391
University of Tübingen · DEGerman Cancer Research Center · DEUniversity Children's Hospital Tübingen · DEDeutschen Konsortium für Translationale Krebsforschung · DEUniversity Children's Hospital Zurich · CHUniversity Hospital of Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

T cell recognition of human leukocyte antigen (HLA)-presented tumor-associated peptides is central for cancer immune surveillance. Mass spectrometry (MS)-based immunopeptidomics represents the only unbiased method for the direct identification and characterization of naturally presented tumor-associated peptides, a key prerequisite for the development of T cell-based immunotherapies. This study reports on the implementation of ion mobility separation-based time-of-flight (TOF

Indexed as

Histocompatibility Antigens Class INeoplasmsAntigens, NeoplasmHistocompatibility Antigens Class IIHLA AntigensHumansMass SpectrometryPeptidesAntigens, NeoplasmHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHLA AntigensPeptides

Identifiers

PMID37978195
PMCPMC10656517
OpenAlexW4388753462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.