Evidence map›Paper›PMID 37978119›Full record

ArticleDermatology and therapy2023

Comorbidity Burden and Treatment Patterns of Psoriasis in Vietnam: Real-World Data from the EXPAND Study.

Hao Trong Nguyen, Anh Tuan Vu, Nhi Thi Uyen Pham, Tu Nguyen Anh Tran, Nguyen Nhat Pham, Huong Thi Thanh Bui, Thuyen Thi Pham, Vi Thi Thuy Dinh, Yen Thi Bui, Thao Thi Phuong Vu

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Hao Trong NguyenHo Chi Minh City Hospital of Dermato-Venereology, 2 Nguyen Thong, Ward Vo Thi Sau, District 3, Ho Chi Minh City, Vietnam. nthao@ump.edu.vn.ORCID http://orcid.org/0000-0002-7732-0497
Anh Tuan VuQuy Hoa National Leprosy Dermatology Hospital, Quy Nhon City, Binh Dinh Province, Vietnam.
Nhi Thi Uyen PhamHo Chi Minh City Hospital of Dermato-Venereology, 2 Nguyen Thong, Ward Vo Thi Sau, District 3, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0002-3976-9963
Tu Nguyen Anh TranHo Chi Minh City Hospital of Dermato-Venereology, 2 Nguyen Thong, Ward Vo Thi Sau, District 3, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0003-1111-9659
Nguyen Nhat PhamHo Chi Minh City Hospital of Dermato-Venereology, 2 Nguyen Thong, Ward Vo Thi Sau, District 3, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0003-2176-0941
Huong Thi Thanh BuiQuy Hoa National Leprosy Dermatology Hospital, Quy Nhon City, Binh Dinh Province, Vietnam.
Thuyen Thi PhamQuy Hoa National Leprosy Dermatology Hospital, Quy Nhon City, Binh Dinh Province, Vietnam.
Vi Thi Thuy DinhQuy Hoa National Leprosy Dermatology Hospital, Quy Nhon City, Binh Dinh Province, Vietnam.
Yen Thi BuiNovartis Vietnam Company Limited, Ho Chi Minh City, Vietnam.
Thao Thi Phuong VuHo Chi Minh City Hospital of Dermato-Venereology, 2 Nguyen Thong, Ward Vo Thi Sau, District 3, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0003-3946-6820
HCMC Hospital of Dermato Venereology · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPsoriasis is a multi-faceted, immune-mediated inflammatory disease associated with a wide range of comorbidities. Real-world data on treatment patterns, comorbidities, and economic burden in patients with psoriasis are needed for comprehensive patient care in Vietnam.

methodsA retrospective chart review study was conducted using secondary data extracted from patients' medical records of two hospitals in Vietnam, with the aim of identifying adult patients with a confirmed diagnosis of psoriasis. The index date was defined as the date of first diagnosis between 1 January 2020 and 31 October 2021. Sociodemographic factors, disease characteristics, comorbidities, medication usage, drug survival, and medication costs were analyzed.

resultsA total of 661 patients were identified (mean ± standard deviation [SD] age 43.5 ± 14.8 years). The most prevalent comorbidity was dyslipidemia (49.6% of patients), followed by hypertension (23.4%), and psoriatic arthritis (10.4%). In total, 44% of patients received biologic therapies. Overall, 66.7% and 54.3% of patients receiving biologic and non-biologic therapies, respectively, had ≥ 1 comorbidity. Only 23.2% of patients with psoriasis-related comorbidities stopped therapy with biologics. Biologics had a longer retention time (17.0 months) than non-biologics (6.0 months) in patients with comorbidities. Patients with comorbidities had significantly higher total annual healthcare costs than those without comorbidities (in US dollars: USD901 vs. USD304; p < 0.001), mainly due to the relatively higher costs associated with the use of biologics.

conclusionPatients with psoriasis in Vietnam experience a high disease and economic burden due to comorbidities. Evidence from this real-world study supports the need for routine monitoring of and an appropriate treatment course for psoriasis-related comorbidities.

Indexed as

ComorbiditiesEconomic burdenPsoriasisRetrospective study

Identifiers

PMID37978119
PMCPMC10689324
OpenAlexW4388749275

What OpenQuestion holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.