Evidence map›Paper›PMID 37975116›Full record

ArticleJournal of diabetes and metabolic disorders2023

Association between iron profile status and insulin resistance in patients with type 2 diabetes mellitus.

Reeba Maryam Sam, Shilpa S Shetty, Suchetha Kumari N, Sharmila Kp, Prajna Bhandary

Abstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Reeba Maryam Sam *KS Hegde Medical Academy, Nitte (Deemed to be University), Mangalore, India.
Shilpa S Shetty *Central Research Laboratory, KS Hegde Medical Academy, Nitte (Deemed to be University), Mangalore, India.
Suchetha Kumari N *Central Research Laboratory, KS Hegde Medical Academy, Nitte (Deemed to be University), Mangalore, India.ORCID 0000-0002-4571-8716
Sharmila KpCentral Research Laboratory, KS Hegde Medical Academy, Nitte (Deemed to be University), Mangalore, India.
Prajna BhandaryCentral Research Laboratory, KS Hegde Medical Academy, Nitte (Deemed to be University), Mangalore, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Individuals' burden of insulin resistance and metabolic syndrome, such as type 2 diabetes mellitus, is increasing. This indicates to intrigue into various facets of prevention, early screening, prognostication and feasible treatment alternatives in this arena. Aim: This study targets to evaluate iron profile status among people diagnosed with type 2 diabetes mellitus and normoglycemic in order to deduce association between iron parameters and insulin resistance, if any exist. Methodology: A case-control study of total 123 subjects, comprising males and females in the age group of 30 - 70 years were recruited for the study. Case group constituted 81 participants who were diagnosed with type 2 diabetes mellitus and control group constituted 42 healthy individuals who attended routine health check-ups in the hospital. Iron profile parameters including Serum Iron, Serum Ferritin, Total Iron binding Capacity and Glycemic profile parameter like fasting blood glucose, serum insulin were estimated. Transferrin saturation and HOMA-IR were calculated. Result: Ferritin and Transferrin saturation was found to be higher in cases than in controls with significance of Conclusion: This study implies that there is a clear link between iron profile status, notably ferritin, and the emergence of insulin resistance, and hence insulin production. This study supports the function of the micronutrient iron in the etiology of type 2 diabetes and its consequences.

Indexed as

DiabetesFerritinInsulinInsulin resistanceIron

Identifiers

PMID37975116
PMCPMC10638270

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