Evidence map›Paper›PMID 37974933›Full record

ArticleMaterials today (Kidlington, England)2020

Nanobiosensing with graphene and carbon quantum dots: Recent advances.

Brandon K Walther, Cerasela Zoica Dinu, Dirk M Guldi, Vladimir G Sergeyev, Stephen E Creager, John P Cooke, Anthony Guiseppi-Elie

Abstract read
In one paragraph

Article in Materials today (Kidlington, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Photonic Nanomaterials for Wearable Health Solutions.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Brandon K WaltherBiosensors and Biochips (C3), Department of Biomedical Engineering and Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-4086-8897
Cerasela Zoica DinuDepartment of Chemical and Biomedical Engineering, West Virginia University, Morgantown, WV 26506, USA.ORCID 0000-0002-6474-6771
Dirk M GuldiDepartment of Chemistry and Pharmacy, Friedrich Alexander University Erlangen-Nürnberg 91058 Erlangen, Germany.ORCID 0000-0002-3960-1765
Vladimir G SergeyevDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1-3, Moscow 119991, Russian Federation.ORCID 0000-0002-8200-5993
Stephen E CreagerDepartment of Chemistry and Department of Materials Science and Engineering, Clemson University, Clemson, SC 29634, USA.ORCID 0000-0002-7412-2268
John P CookeBiosensors and Biochips (C3), Department of Biomedical Engineering and Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-0033-9138
Anthony Guiseppi-ElieBiosensors and Biochips (C3), Department of Biomedical Engineering and Department of Electrical and Computer Engineering, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-3218-9285

Funding

Reversal of Heart Failure: Role of Vascular RecoveryR01HL148338 · NHLBI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI CHEN, KAIFU, COOKE, JOHN P · 2020 to 2023
$2.8M
Role of S-nitrosylation in TransdifferentiationR01HL133254 · NHLBI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI CHEN, KAIFU, COOKE, JOHN P · 2018 to 2021
$1.6M
NHLBI NIH HHS R01 HL133254NHLBI NIH HHS R01 HL148338
6 · The paper itself

Abstract

Graphene and carbon quantum dots (GQDs and CQDs) are relatively new nanomaterials that have demonstrated impact in multiple different fields thanks to their unique quantum properties and excellent biocompatibility. Biosensing, analyte detection and monitoring wherein a key feature is coupled molecular recognition and signal transduction, is one such field that is being greatly advanced by the use of GQDs and CQDs. In this review, recent progress on the development of biotransducers and biosensors enabled by the creative use of GQDs and CQDs is reviewed, with special emphasis on how these materials specifically interface with biomolecules to improve overall analyte detection. This review also introduces nano-enabled biotransducers and different biosensing configurations and strategies, as well as highlights key properties of GQDs and CQDs that are pertinent to functional biotransducer design. Following relevant introductory material, the literature is surveyed with emphasis on work performed over the last 5 years. General comments and suggestions to advance the direction and potential of the field are included throughout the review. The strategic purpose is to inspire and guide future investigations into biosensor design for quality and safety, as well as serve as a primer for developing GQD- and CQD-based biosensors.

Identifiers

PMID37974933
PMCPMC10653125

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.