Evidence map›Paper›PMID 37974620›Full record

ReviewACS pharmacology & translational science2023

A Reappraisal of the Antiviral Properties of and Immune Regulation through Dietary Phytochemicals.

Mony Thakur, Mona Singh, Sandeep Kumar, Ved Prakash Dwivedi, Tikam Chand Dakal, Vinod Yadav

Open access · greenAbstract readReview
In one paragraph

Review in ACS pharmacology & translational science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Phytochemicals in Drug Discovery-A Confluence of Tradition and Innovation.International journal of molecular sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Mony ThakurDepartment of Microbiology, Central University of Haryana, Mahendergarh, Haryana 123031, India.
Mona SinghDepartment of Obstetrics and Gynaecology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.
Sandeep KumarDivision of Cell Biology and Immunology, Council of Scientific and Industrial Research - Institute of Microbial Technology, Chandigarh 160036, India.
Ved Prakash DwivediInternational Centre for Genetic Engineering and Biotechnology, ICGEB Campus, Aruna Asaf Ali Marg, New Delhi 110067, India.
Tikam Chand DakalGenome and Computational Biology Lab, Department of Biotechnology, Mohanlal Sukhadia University, Udaipur, Rajasthan 313001, India.ORCID https://orcid.org/0000-0002-9248-7391
Vinod YadavDepartment of Microbiology, Central University of Haryana, Mahendergarh, Haryana 123031, India.
Central University of Haryana · INInstitute of Microbial Technology · INInternational Centre for Genetic Engineering and Biotechnology · INMedical College of Wisconsin · USMohanlal Sukhadia University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present era of the COVID-19 pandemic, viral infections remain a major cause of morbidity and mortality worldwide. In this day and age, viral infections are rampant and spreading rapidly. Among the most aggressive viral infections are ebola, AIDS (acquired immunodeficiency syndrome), influenza, and SARS (severe acute respiratory syndrome). Even though there are few treatment options for viral diseases, most of the antiviral therapies are ineffective owing to frequent mutations, the development of more aggressive strains, drug resistance, and possible side effects. Traditionally, herbal remedies have been used by healers, including for dietary and medicinal purposes. Many clinical and scientific studies have demonstrated the therapeutic potential of plant-derived natural compounds. Because of unsafe practices like blood transfusions and organ transplants from infected patients, medical supply contamination. Our antiviral therapies cannot achieve sterile immunity, and we have yet to find a cure for these pernicious infections. Herbs have been shown to improve therapeutic efficacy against a wide variety of viral diseases because of their high concentration of immunomodulatory phytochemicals (both immunoinhibitory and anti-inflammatory). Combined with biotechnology, this folk medicine system can lead to the development of novel antiviral drugs and therapies. In this Review, we will summarize some selected bioactive compounds with probable mechanisms of their antiviral actions, focusing on the immunological axis of these compounds.

Identifiers

PMID37974620
PMCPMC10644413
OpenAlexW4387477029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.