Evidence map›Paper›PMID 37974551›Full record

Trial reportBrain and behavior2023

The effect of transcutaneous auricular vagus nerve stimulation on cycling ergometry and recovery in healthy young individuals.

Sefa Haktan Hatik, Mesut Arslan, Ömer Demirbilek, Ali Veysel Özden

4 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06531954 phase2completednot on this map

Comparison Of Breathing Exercises and Auricular Vagus Nerve Stimulation Effects On Autonomic Nervous System Activity and Respiratory Functions In Healthy Adults

TypeinterventionalSponsorIstanbul Medipol University HospitalRan2021 to 2023Enrolled88ConditionsBreathing Exercises, Auricular Vagus Nerve Stimulation, Autonomic Nervous SystemArmsVagus nerve stimulation, Breathing exercise
NCT06985043 nacompletednot on this mapstarted 2025, after this paper: background citation

The Effect of Vagus Nerve Stimulation on Lower Limb Muscle Strength and Balance in Nonelite Athletes

TypeinterventionalSponsorBahçeşehir UniversityRan2025 to 2025Enrolled30ConditionsVagus Nerve Stimulations, Muscle Strength, BalanceArmsAuricular vagus nerve stimulation (AVNS)
NCT07371676 nacompletednot on this mapstarted 2024, after this paper: background citation

Acute Effects of Post-Exercise Vagus Nerve Stimulation on the Autonomic Nervous System and Recovery in Healthy Young Adults

TypeinterventionalSponsorIstanbul Gelisim UniversityRan2024 to 2025Enrolled60ConditionsAuricular Vagus Nerve Stimulation, Transcutaneous, RecoveryArmsStimulation
NCT07594873 nacompletednot on this mapstarted 2026, after this paper: background citation

The Acute Effects of Controlled Breathing Exercises and Music Therapy on the Autonomic Nervous System in Anxious Individuals: A Randomized Controlled Study

TypeinterventionalSponsorIstanbul Health and Technology UniversityRan2026 to 2026Enrolled30ConditionsAnxious IndividualsArmsControlled Breathing Exercises Group, Music-Assisted Breathing Group
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Transcutaneous vagus nerve stimulation and exercise-induced autonomic regulation: a systematic review.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sefa Haktan HatikDepartment of Health Care Services, Türkeli Vocational School, Sinop University, Sinop, Turkey.ORCID 0000-0003-0517-4600
Mesut ArslanPhysiotherapy and Rehabilitation Department, Health Sciences Faculty, Bitlis Eren University, Bitlis, Turkey.
Ömer DemirbilekDepartment of Emergency and Disaster Management, Türkeli Vocational School, Sinop University, Sinop, Turkey.
Ali Veysel ÖzdenPhysiotherapy and Rehabilitation Department, Health Sciences Faculty, Bahçeşehir University, Istanbul, Turkey.
Sinop University · TRBahçeşehir University · TRBitlis Eren University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is aimed to examine the potential benefits and effects of the use of transcutaneous auricular vagus nerve stimulation (VNS) for sporting purposes on recovery, fatigue, and sportive performance level.

methodsIn this study, 90 people between the ages of 18-23 were participated. They were randomly divided into three groups as bilateral sham, unilateral left, and bilateral VNS. A 4-day protocol was applied to the participants. Cycling exercise was performed with maximum performance for 30 min under the same watt load. Pulse, systolic and diastolic blood pressure, distance, pain, fatigue, lactic acid level, and autonomic nervous system were evaluated.

resultsWithin the groups, there was a statistically significant difference between the data (p < .05) except for the distance covered parameter. When we compare the groups, in addition to the distance traveled in all groups, there is no statistically significant difference in the 1st day 1st measurement and 2nd measurement data of all parameters (p > .05 When we compared the data according to days, there was a statistically significant difference between bilateral stimulation (BS) and unilateral stimulation, only pain and fatigue levels (p < .05).

conclusionIn our study, we saw that BS application gave positive results in reducing pain and fatigue due to cycling exercise compared to other applications. Similar results were obtained when we evaluated the data on a daily basis. We believe that VNS will be beneficial in reducing pain and fatigue, especially during and after the competition halftime.

Indexed as

Transcutaneous Electric Nerve StimulationVagus Nerve StimulationAdolescentAutonomic Nervous SystemHeart RateHumansPainVagus NerveYoung Adultauricularcycling ergometryrecoverytranscutaneousvagus nerve stimulation

Identifiers

PMID37974551
PMCPMC10726880
OpenAlexW4388768776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.