Evidence map›Paper›PMID 37974189›Full record

Trial reportBMC medicine2023

Mood, Activity Participation, and Leisure Engagement Satisfaction (MAPLES): results from a randomised controlled pilot feasibility trial for low mood in acquired brain injury.

Andrea Kusec, Fionnuala C Murphy, Polly V Peers, Ron Bennett, Estela Carmona, Aleksandra Korbacz, Cara Lawrence, Emma Cameron, Andrew Bateman, Peter Watson and 3 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03874650 (Mood, Activity Participation, and Leisure Engagement Satisfaction), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03874650 nacompletednot on this map

Mood, Activity Participation, and Leisure Engagement Satisfaction (MAPLES): A Pilot Feasibility Study for Low Mood in Acquired Brain Injury

TypeinterventionalSponsorUniversity of CambridgeRan2019 to 2021Enrolled60ConditionsAcquired Brain Injury, DepressionArmsActivity Planning Group, Activity Engagement Group, Waitlist Group
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Andrea KusecMRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK. andrea.kusec@ndcn.ox.ac.uk.ORCID 0000-0003-0128-4677
Fionnuala C MurphyMRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Polly V PeersMRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Ron Bennett *MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Estela CarmonaMRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Aleksandra KorbaczMRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Cara LawrenceSchool of Allied Health, Anglia Ruskin University, Cambridge, UK.
Emma CameronUniversity College London Hospitals NHS Foundation Trust, London, UK.
Andrew BatemanSchool of Health and Social Care, University of Essex, Colchester, UK.
Peter WatsonMRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
Judith AllansonCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Pieter duToitSchool of Health and Social Care, University of Essex, Colchester, UK.
Tom ManlyMRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, UK.
MRC Cognition and Brain Sciences Unit · GBUniversity of Essex · GBAnglia Ruskin University · GBCambridge University Hospitals NHS Foundation Trust · GBUniversity College London Hospitals NHS Foundation Trust · GB

Funding

Medical Research Council MC_UU_00030/11Medical Research Council SUAG/049
6 · The paper itself

Abstract

backgroundAcquired brain injury (ABI) is linked to increased depression risk. Existing therapies for depression in ABI (e.g., cognitive behavioural therapy) have mixed efficacy. Behavioural activation (BA), an intervention that encourages engaging in positively reinforcing activities, shows promise. The primary aims were to assess feasibility, acceptability, and potential efficacy of two 8-week BA groups.

methodsAdults (≥ 18 years) recruited from local ABI services, charities, and self-referral via social media were randomised to condition. The Activity Planning group (AP; "traditional" BA) trained participants to plan reinforcing activities over 8 weeks. The Activity Engagement group (AE; "experiential" BA) encouraged engagement in positive activities within session only. Both BA groups were compared to an 8-week Waitlist group (WL). The primary outcomes, feasibility and acceptability, were assessed via recruitment, retention, attendance, and qualitative feedback on groups. The secondary outcome, potential efficacy, was assessed via blinded assessments of self-reported activity levels, depression, and anxiety (at pre- and post-intervention and 1 month follow-up) and were compared across trial arms. Data were collected in-person and remotely due to COVID-19.

resultsN = 60 participants were randomised to AP (randomised n = 22; total n = 29), AE (randomised n = 22; total n = 28), or re-randomised following WL (total n = 16). Whether in-person or remote, AP and AE were rated as similarly enjoyable and helpful. In exploring efficacy, 58.33% of AP members had clinically meaningful activity level improvements, relative to 50% AE and 38.5% WL. Both AP and AE groups had depression reductions relative to WL, but only AP participants demonstrated anxiety reductions relative to AE and WL. AP participants noted benefits of learning strategies to increase activities and learning from other group members. AE participants valued social discussion and choice in selecting in-session activities.

conclusionsBoth in-person and remote group BA were feasible and acceptable in ABI. Though both traditional and experiential BA may be effective, these may have different mechanisms.

trial registrationClinicaltrials.gov, NCT03874650. Protocol version 2.3, May 26 2020.

Indexed as

AcerBrain InjuriesCognitive Behavioral TherapyAdultFeasibility StudiesHumansPersonal SatisfactionPilot ProjectsAcquired brain injuryDepressionExecutive functionFeasibility trialNeuropsychological rehabilitationRandomised trialTraumatic brain injury

Identifiers

PMID37974189
PMCPMC10655452
OpenAlexW4388730107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.