Evidence map›Paper›PMID 37974125›Full record

Trial reportBMC infectious diseases2023

Near complete genome sequences from Southern Vietnam revealed local features of genetic diversity and intergenerational changes in SARS- CoV-2 variants in 2020-2021.

Anna S Gladkikh, Thang M Cao, Ekaterina O Klyuchnikova, Manh H Dao, Alena A Sharova, Vasilina D Melnichenko, Margarita R Popova, Tatiana V Arbuzova, Valeriya A Sbarzaglia, Nadezhda A Tsyganova and 2 more

Erratum issuedOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Anna S GladkikhSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Thang M CaoPasteur Institute in Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Ekaterina O KlyuchnikovaSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia. ekaterina.ibg@gmail.com.
Manh H DaoPasteur Institute in Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Alena A SharovaSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Vasilina D MelnichenkoSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Margarita R PopovaSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Tatiana V ArbuzovaSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Valeriya A SbarzagliaSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Nadezhda A TsyganovaSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Edward RamsaySaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Vladimir G DedkovSaint Petersburg Pasteur Institute, 14 Mira Street, Saint Petersburg, 197101, Russia.
Saint Petersburg Pasteur Institute · RUInstitut Pasteur in Ho Chi Minh City · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince its beginnings in 2019, the COVID-19 pandemic is still a problem of global medical concern. Southern Vietnam is one of the country's vast regions, including 20 provinces and the densely populated metropolis Ho Chi Minh City. A randomized retrospective study was performed to investigate the epidemiology and genetic diversity of COVID-19. Whole-genome sequencing of 126 SARS-CoV-2 samples collected from Southern Vietnam between January 2020 and December 2021 revealed the main circulating variants and their distribution.

methodsEpidemiological data were obtained from the Department of Preventive Medicine of the Vietnamese Ministry of Health. To identify circulating variants, RNA, extracted from 126 nasopharyngeal swabs of patients with suspected COVID-19 were sequenced on Illunina MiSeq to obtain near complete genomes SARS-CoV-2.

resultsDue to the effectiveness of restrictive measures in Vietnam, it was possible to keep incidence at a low level. The partial relaxation of restrictive measures, and the spread of Delta lineages, contributed to the beginning of a logarithmic increase in incidence. Lineages 20A-H circulated in Southern Vietnam during 2020. Spread of the Delta lineage in Southern Vietnam began in March 2021, causing a logarithmic rise in the number of COVID-19 cases.

conclusionsPandemic dynamics in Southern Vietnam feature specific variations in incidence, and these reflect the success of the restrictive measures put in place during the early stages of the pandemic.

Indexed as

COVID-19SARS-CoV-2Genetic VariationHumansPandemicsRetrospective StudiesVietnamCOVID-19MorbidityNGSSARS-CoV-2 lineagesVietnam

Identifiers

PMID37974125
PMCPMC10655423
OpenAlexW4388773095

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.