Evidence map›Paper›PMID 37973848›Full record

ArticleScientific reports2023

New insights into the genetic predisposition of brucellosis and its effect on the gut and vaginal microbiota in goats.

Ahmed M Sallam, Ibrahim Abou-Souliman, Henry Reyer, Klaus Wimmers, Alaa Emara Rabee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ahmed M SallamAnimal and Poultry Breeding Department, Desert Research Center, Cairo, Egypt. ahmedsallam2@gmail.com.
Ibrahim Abou-SoulimanAnimal and Poultry Breeding Department, Desert Research Center, Cairo, Egypt.
Henry ReyerResearch Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196, Dummerstorf, Germany.
Klaus WimmersResearch Institute for Farm Animal Biology (FBN), Wilhelm-Stahl-Allee 2, 18196, Dummerstorf, Germany.
Alaa Emara RabeeAnimal and Poultry Nutrition Department, Desert Research Center, Cairo, Egypt.
Desert Research Center · EGResearch Institute for Farm Animal Biology (FBN) · DE

Funding

Science and Technology Development Fund 4321
6 · The paper itself

Abstract

Goats contribute significantly to the global food security and industry. They constitute a main supplier of meat and milk for large proportions of people in Egypt and worldwide. Brucellosis is a zoonotic infectious disease that causes a significant economic loss in animal production. A case-control genome-wide association analysis (GWAS) was conducted using the infectious status of the animal as a phenotype. The does that showed abortion during the last third period of pregnancy and which were positive to both rose bengal plate and serum tube agglutination tests, were considered as cases. Otherwise, they were considered as controls. All animals were genotyped using the Illumina 65KSNP BeadChip. Additionally, the diversity and composition of vaginal and fecal microbiota in cases and controls were investigated using PCR-amplicone sequencing of the V4 region of 16S rDNA. After applying quality control criteria, 35,818 markers and 66 does were available for the GWAS test. The GWAS revealed a significantly associated SNP (P = 5.01 × 10

Indexed as

BrucellosisMicrobiotaAnimalsBacteriaFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyGoatsHumansPregnancyUbiquitin ThiolesteraseUbiquitin ThiolesteraseUSP18 protein, human

Identifiers

PMID37973848
PMCPMC10654701
OpenAlexW4388718754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.