Evidence map›Paper›PMID 37973653›Full record

ArticleAbdominal radiology (New York)2024

Proposal for a new morphological "combined type" of gallbladder cancer: description of radiopathological characteristics and comparison with other morphological types.

Manika Chhabra, Daneshwari Kalage, Pankaj Gupta, Ruby Siddiqui, Shravya Singh, Thakur Deen Yadav, Vikas Gupta, Lileswar Kaman, Harjeet Singh, Santosh Irrinki and 7 more

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Article in Abdominal radiology (New York), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Gallbladder cancer: Progress in the Indian subcontinent.World journal of clinical oncology · 2024
    Review
  4. Article
  5. Article
4 · The record

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5 · Who and what money

Authors and funding

17 authors.

Manika Chhabra *Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Daneshwari Kalage *Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Pankaj GuptaDepartment of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Pankajgupta959@gmail.com.ORCID 0000-0003-3914-3757
Ruby SiddiquiDepartment of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Shravya SinghDepartment of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Thakur Deen YadavDepartment of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Vikas GuptaDepartment of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Lileswar KamanDepartment of General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Harjeet SinghDepartment of Surgical Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Santosh IrrinkiDepartment of General Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Chandan DasDepartment of Clinical Hematology and Medical Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Gaurav PrakashDepartment of Clinical Hematology and Medical Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Parikshaa GuptaDepartment of Cytology and Gynecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Uma Nahar SaikiaDepartment of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Ritambhra NadaDepartment of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Usha DuttaDepartment of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Manavjit Singh SandhuDepartment of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the radiopathological characteristics of a new morphological "combined type" of gallbladder cancer (GBC) and compare it with the mass replacing gallbladder and thickening types of GBC. MATERIALS AND

methodsThe imaging and pathological details of consecutive patients with GBC between August 2020 and December 2022 were retrospectively reviewed. Two radiologists reviewed computed tomography/magnetic resonance imaging in consensus for the morphological type of GBC. The radiologists classified GBC as mass replacing gallbladder, wall thickening, and combined type. The combined type was defined as a mass arising from the thickened wall of an adequately distended gallbladder that extended exophytically into the adjacent liver parenchyma. The presence of calculi, site, and size of lesion, biliary/portal vein involvement, liver, lymph node, and omental metastases was compared among the various types. The pathological characteristics were also compared.

resultsOf the 481 patients (median age 55 years, 63.2% females) included in the study, mass replacing gallbladder, wall thickening, and combined-type GBC were seen in 42.8% (206/481), 40.5% (195/481), and 16.6% (80/481) of patients, respectively. In the combined type of GBC, biliary/portal vein involvement was seen in 63.7% (51/80) and 7.5% (6/80) of patients. Liver, lymph node, and omental metastases were seen in 67.5% (54/80), 40% (32/80), and 41.2% (33/80) patients, respectively. Liver metastases were significantly more common in the combined type (p = 0.002). There were no significant differences in pathological characteristics among the various types.

conclusionCombined-type GBC is less common than the mass replacing gallbladder and thickening types and is associated with a higher risk of liver metastases.

Indexed as

Gallbladder NeoplasmsLiver NeoplasmsFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesGallbladderGallbladder cancerMagnetic resonance imagingMorphologyMultidetector computed tomography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.