Evidence map›Paper›PMID 37973550›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Urethral Microenvironment Adapted Sodium Alginate/Gelatin/Reduced Graphene Oxide Biomimetic Patch Improves Scarless Urethral Regeneration.

Liyang Wang, Kai Wang, Ming Yang, Xi Yang, Danyang Li, Meng Liu, Changmei Niu, Weixin Zhao, Wenyao Li, Qiang Fu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Liyang WangThe Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, P. R. China.
Kai WangClinical Research Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, 200233, P. R. China.
Ming YangThe Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, P. R. China.
Xi YangNovaprint Therapeutics Suzhou Co., Ltd, Suzhou, 215000, P. R. China.
Danyang LiThe Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, P. R. China.
Meng LiuThe Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, P. R. China.
Changmei NiuNovaprint Therapeutics Suzhou Co., Ltd, Suzhou, 215000, P. R. China.
Weixin ZhaoWake Forest Institute for Regenerative Medicine, Winston-Salem, NC, 27155, USA.
Wenyao LiSchool of Materials Science and Engineering, Shanghai University of Engineering Science, Shanghai, 201620, P. R. China.
Qiang FuThe Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, P. R. China.ORCID 0000-0001-5670-024X
Kaile ZhangThe Department of Urology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Jiao Tong University, Shanghai, 200233, P. R. China.
Shanghai Jiao Tong University · CNShanghai University of Engineering Science · CNSuzhou Research Institute · CNForest Institute · US

Funding

Class III Peak Discipline of Shanghai-Materials Science and Engineering (High-Energy Beam Intelligent Processing and Green Manufacturing)Jiangsu Key Technology Research Development Program BE2017664National Key Research and Development Program of China 2018YFA0703100National Natural Science Foundation of China 62374107National Natural Science Foundation of China 81772135National Natural Science Foundation of China 82072217Natural Science Foundation of Shanghai 20ZR1442100Shanghai health committee 20184Y0053Shanghai Jiao Tong University Biomedical Engineering Cross Research Foundation YG2017QN15Shanghai Jiao Tong University Biomedical Engineering Cross Research Foundation YG2022ZD022Shanghai Local Universities Capacity Building Project of Science and Technology Innovation Action Program 21010501700The Talent Program of Shanghai University of Engineering Science QNTD202104
6 · The paper itself

Abstract

The nasty urine microenvironment (UME) is an inherent obstacle that hinders urethral repair due to fibrosis and swelling of the oftentimes adopted hydrogel-based biomaterials. Here, using reduced graphene oxide (rGO) along with double-freeze-drying to strengthen a 3D-printed patch is reported to realize scarless urethral repair. The sodium alginate/gelatin/reduced graphene oxide (SA/Gel/rGO) biomaterial features tunable stiffness, degradation profile, and anti-fibrosis performance. Interestingly, the 3D-printed alginate-containing composite scaffold is able to respond to Ca

Indexed as

AlginatesGraphiteTissue ScaffoldsBiocompatible MaterialsBiomimeticsFibrosisGelatinHumansRegenerationAlginatesBiocompatible MaterialsGelatingraphene oxideGraphite3D printinghydrogelsreduced graphene oxideurethral reconstructionurethral stricture

Identifiers

PMID37973550
PMCPMC10787096
OpenAlexW4388769290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.