ArticleThe American journal of tropical medicine and hygiene2023
Characterization of Dengue Virus Serotype 2 Cosmopolitan Genotype Circulating in Colombia.
Article in The American journal of tropical medicine and hygiene, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- Severe Dengue and Dengue-Malaria Coinfection: A Case Series from a Referral Hospital in Montería, Colombia.Clinics and practice · 2026Article
- Unexpected diversification of DENV2 genotype III in Colombia: New Insights and application of the globalized nomenclature.PloS one · 2026Article
- Tracing Dengue's Evolutionary and Phylogenetic Pathways.Current topics in microbiology and immunology · 2026Review
- Emergence of Dengue Virus Serotype 2 Cosmopolitan Genotype in Costa Rica.The American journal of tropical medicine and hygiene · 2025Article
- Article
- Malaria, Dengue Fever, and Leptospirosis in the Urabá Antioqueño Region, Colombia: Etiological and Molecular Characterization among Patients with Acute Undifferentiated Febrile Illness.The American journal of tropical medicine and hygiene · 2025Article
- Genotypic diversity and molecular characterization of DENV-2 in a Peruvian endemic region from 2016 to 2022: displacement of American/Asian genotype.Frontiers in microbiology · 2025Article
- Co-Circulation of 2 Oropouche Virus Lineages, Amazon Basin, Colombia, 2024.Emerging infectious diseases · 2024Article
- Genomics for Arbovirus Surveillance: Considerations for Routine Use in Public Health Laboratories.Viruses · 2024Review
- Mayaro Virus as the cause of Acute Febrile Illness in the Colombian Amazon Basin.Frontiers in microbiology · 2024Article
- Cryptic transmission and novel introduction of Dengue 1 and 2 genotypes in Colombia.Virus evolution · 2024Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dengue virus (DENV) is the etiological agent of dengue fever (DF), which is among the most prevalent vector-borne diseases in the tropics. In 2022, the Colombian health surveillance system reported more than 69,000 cases of DF. As part of a hospital-based fever surveillance study, acute-phase sera were collected from 4,545 patients with suspected dengue between 2020 and 2023 in three municipalities of Colombia. Combined reverse transcription-polymerase chain reaction and antigen rapid testing confirmed that 376 patients (8.3%) had DF. The virus was isolated in cell culture from 166 of these patients (44.1%), and genome sequencing was performed successfully on 122 (73.5%). Three DENV serotypes (1, 2, and 3) were identified. Phylogenetic analyses of the DENV-2 sequences revealed that 42 of 50 of the isolates (84%) belonged to the DENV-2 cosmopolitan genotype lineage, clustering with sequences from Asia, Peru, and Brazil. We report the detection, isolation, and whole-genome sequencing (11 Kb) of the DENV-2 cosmopolitan genotype and its recent introduction to Colombia.
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