ArticleNeuropsychology2024
Identifying and distinguishing cognitive profiles among virally suppressed people with HIV.
Article in Neuropsychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Cognitive and fine motor performance in people above 65 years of age with and without HIV.Scientific reports · 2026Article
- Serum but not cerebrospinal fluid biomarkers are associated with domain-specific cognitive performance in PWH.Journal of neurovirology · 2026Article
- Cerebrospinal fluid markers of alzheimer's pathology relate to aMCI among people with HIV.BMC neurology · 2026Article
- Osteopontin knockdown reverses HIV-induced cognitive deficits and influences motivation-related behavior.Brain, behavior, and immunity · 2026Article
- International application of an optimized harmonization approach for longitudinal cognitive data in people with HIV.Journal of clinical epidemiology · 2025Article
- Development of a refined harmonization approach for longitudinal cognitive data in people with HIV.Journal of clinical epidemiology · 2025Article
- Imaging the translocator protein 18 kDa within cognitive control and declarative memory circuits in virally suppressed people with HIV.AIDS (London, England) · 2025Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveCognitive deficits are common among people with HIV (PWH), even when virally suppressed. We identified cognitive profiles among virally suppressed PWH and determined how sociodemographic, clinical/behavioral, and HIV disease characteristics distinguish profile membership.
methodParticipants included 704 virally suppressed PWH (
resultsSix cognitive profiles were identified: (a) "unimpaired" (19.9%); (b) weakness in verbal learning and memory (15.5%); (c) weakness in executive function and learning (25.8%); (d) weakness in motor, processing speed, and executive function (8.1%); (e) impaired learning and recall with weak-to-impaired motor, processing speed, and executive function (13.1%); (f) global deficits (17.6%). The most discriminative sociodemographic, clinical/behavioral, and HIV disease characteristics varied by profile with self-reported mood symptoms and cognitive/functional difficulties (e.g., language/communication, memory, and overall everyday function complaints) most consistently associated with profile membership.
conclusionsCognitive profiles and their associated factors among PWH are heterogeneous, but learning/memory deficits were most common and self-reported mood, and cognitive/functional difficulties were most consistently related to profile membership. This heterogeneity in cognitive profiles and their correlates in PWH suggests that differing mechanisms contribute to cognitive deficits and, thus, underscores the need for personalized risk reduction and therapeutic strategies among PWH. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
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Registered trials
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