Evidence map›Paper›PMID 37971575›Full record

ArticleAmino acids2023

Synthesis and glutathione peroxidase (GPx)-like activity of selenocystine (SeC) bioconjugates of biotin and lipoic acid.

Shakti K Maurya, Abhishek Tripathi, Selvakumar Karuthapandi, Harkesh B Singh

Abstract read
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In one paragraph

Article in Amino acids, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shakti K MauryaDepartment of Chemistry, Indian Institute of Technology Bombay, Mumbai, 400076, India.
Abhishek TripathiDepartment of Chemistry, Indian Institute of Technology Bombay, Mumbai, 400076, India.
Selvakumar KaruthapandiDepartment of Chemistry, School of Advanced Sciences, VIT-AP University, Amaravati, AP, 522241, India. selvakumar.k@vitap.ac.in.
Harkesh B SinghDepartment of Chemistry, Indian Institute of Technology Bombay, Mumbai, 400076, India. chhbsia@chem.iitb.ac.in.
Indian Institute of Technology Bombay · INVIT-AP University

Funding

Science and Engineering Research Board 501100001843
6 · The paper itself

Abstract

The conjugation of active biomolecules provides insight into their bioreactivity, leading to many applications in biotechnology and materials science. Herein, we report L-selenocystine (SeC) bioconjugates of lipoic acid (universal antioxidant) and biotin (Vitamin-H). The SeC-bioconjugates, SeC-Biotin (1) and SeC-Lipoic acid (2) were synthesized using solid phase peptide synthesis (SPPS) method and were characterized by multinuclear 1D (

Indexed as

Organoselenium CompoundsThioctic AcidAntioxidantsBiotinCystineGlutathioneGlutathione PeroxidaseAntioxidantsBiotinCystineGlutathioneGlutathione PeroxidaseOrganoselenium CompoundsselenocystineThioctic AcidBioconjugatesBiotinEbselenGPx activityLipoic acidSelenocystine (SeC)

Identifiers

PMID37971575
OpenAlexW4388724855

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.