ArticleJournal of the American Chemical Society2023
Ring Opening of Glycerol Cyclic Phosphates Leads to a Diverse Array of Potentially Prebiotic Phospholipids.
Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Article
- Autonomous migration of a phosphate group along glycerol and inositol scaffolds driven by a phosphodiester reaction cycle.Nature chemistry · 2026Article
- From searching for extraterrestrial biosignatures to exploring the origins of life: A prebiotic chemistry perspective.Fundamental research · 2026Review
- Hydroxy acid conjugation to lipids increases structural and hydrolytic stability.Nature communications · 2026Article
- Chemical Routes to Primitive Membranes: Prebiotic Lipid Formation at the Origin of Life.Life (Basel, Switzerland) · 2026Review
- Pathway selection between click and acyl transfer reactions driven by aminoacyl phosphates.Nature communications · 2026Article
- Tailored Phosphate Leaving Groups Direct Pathway-Dependent Self-Assembly.Journal of the American Chemical Society · 2026Article
- Tertiary alkylamine-functionalized polyaspartamides with potent antibacterial activity.Bioactive materials · 2026Article
- The astrochemical evolutionary traits of phospholipid membrane homochirality.Nature reviews. Chemistry · 2024Review
- Active droplets through enzyme-free, dynamic phosphorylation.Nature communications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phospholipids are the primary constituents of cell membranes across all domains of life, but how and when phospholipids appeared on early Earth remains unknown. Pressingly, most prebiotic syntheses of complex phospholipids rely upon substrates not yet shown to have been available on early Earth. Here, we describe potentially prebiotic syntheses of a diverse array of complex phospholipids and their building blocks. First, we show that choline could have been produced on early Earth by stepwise
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.