Evidence map›Paper›PMID 37971305›Full record

ArticleNucleic acids research2024

Cistrome Data Browser: integrated search, analysis and visualization of chromatin data.

Len Taing, Ariaki Dandawate, Sehi L'Yi, Nils Gehlenborg, Myles Brown, Clifford A Meyer

Abstract read
In one paragraph

Article in Nucleic acids research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Len TaingCenter for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA.
Ariaki DandawateDepartment of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA.
Sehi L'YiDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-7720-2848
Nils GehlenborgDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0327-8297
Myles BrownCenter for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID 0000-0002-8213-1658
Clifford A MeyerDepartment of Data Science, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID 0000-0002-8321-2839

Funding

Developing Informatics Technologies to Model Cancer Gene RegulationU24CA237617 · NCI · DANA-FARBER CANCER INST · PI MEYER, CLIFFORD · 2019 to 2023
$3.6M
NCI NIH HHS U24 CA237617NIH HHS U24 CA237617
6 · The paper itself

Abstract

The Cistrome Data Browser is a resource of ChIP-seq, ATAC-seq and DNase-seq data from humans and mice. It provides maps of the genome-wide locations of transcription factors, cofactors, chromatin remodelers, histone post-translational modifications and regions of chromatin accessible to endonuclease activity. Cistrome DB v3.0 contains approximately 45 000 human and 44 000 mouse samples with about 32 000 newly collected datasets compared to the previous release. The Cistrome DB v3.0 user interface is implemented as a single page application that unifies menu driven and data driven search functions and provides an embedded genome browser, which allows users to find and visualize data more effectively. Users can find informative chromatin profiles through keyword, menu, and data-driven search tools. Browser search functions can predict the regulators of query genes as well as the cell type and factor dependent functionality of potential cis-regulatory elements. Cistrome DB v3.0 expands the display of quality control statistics, incorporates sequence logos into motif enrichment displays and includes more expansive sample metadata. Cistrome DB v3.0 is available at http://db3.cistrome.org/browser.

Indexed as

ChromatinDatabases, ProteinGenomicsSoftwareAnimalsData VisualizationHistonesHumansInternetMiceSequence Analysis, DNATranscription FactorsChromatinHistonesTranscription Factors

Identifiers

PMID37971305
PMCPMC10767960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.