Evidence map›Paper›PMID 37971259›Full record

ArticleMicrobiology spectrum2023

Cytomegalovirus-vectored COVID-19 vaccines elicit neutralizing antibodies against the SARS-CoV-2 Omicron variant (BA.2) in mice.

Jian Liu, Dabbu Kumar Jaijyan, Yanling Chen, Changcan Feng, Shaomin Yang, Zhenglong Xu, Nichun Zhan, Congming Hong, Shuxuan Li, Tong Cheng and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jian LiuSchool of Biological Sciences and Biotechnology, Minnan Normal University , Zhangzhou, Fujian, China.ORCID 0000-0003-3622-2767
Dabbu Kumar JaijyanDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers-New Jersey Medical School , Newark, New Jersey, USA.
Yanling ChenSchool of Biological Sciences and Biotechnology, Minnan Normal University , Zhangzhou, Fujian, China.
Changcan FengSchool of Biological Sciences and Biotechnology, Minnan Normal University , Zhangzhou, Fujian, China.
Shaomin YangShenzhen Municipal Key Laboratory for Pain Medicine, Department of Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital , Shenzhen, Guangdong, China.ORCID 0000-0001-7932-4777
Zhenglong XuSchool of Biological Sciences and Biotechnology, Minnan Normal University , Zhangzhou, Fujian, China.
Nichun ZhanSchool of Biological Sciences and Biotechnology, Minnan Normal University , Zhangzhou, Fujian, China.
Congming HongState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University , Xiamen, Fujian, China.
Shuxuan LiState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University , Xiamen, Fujian, China.
Tong ChengState Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Life Sciences, Xiamen University , Xiamen, Fujian, China.
Hua ZhuDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers-New Jersey Medical School , Newark, New Jersey, USA.ORCID 0000-0002-6087-3175
Zhangzhou Normal University · CNXiamen University · CNRutgers, The State University of New Jersey · USUnion Hospital · CN

Funding

Fujian Provincial Department of Science and Technology () 2020J05166Minnan Normal University KJ18022, MSGJB2022012
6 · The paper itself

Abstract

importanceCytomegalovirus (CMV) has been used as a novel viral vector for vaccine development and gene therapy. Coronavirus disease 2019 is an infectious disease caused by the SARS-CoV-2 virus, which is highly mutable and is still circulating globally. The study showed that the CMV viral vector caused transient systemic infection and induced robust transgene expression

Indexed as

COVID-19Cytomegalovirus InfectionsAnimalsAntibodies, NeutralizingAntibodies, ViralCOVID-19 VaccinesCytomegalovirusHumansMiceSARS-CoV-2Antibodies, NeutralizingAntibodies, ViralCOVID-19 Vaccinescytomegalovirusimmunogenicity evaluationSARS-CoV-2variant of concernviral vector-based vaccine

Identifiers

PMID37971259
PMCPMC10883801
OpenAlexW4388734564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.