Evidence map›Paper›PMID 37970049›Full record

ArticleACS omega2023

Activation of SIRT6 Deacetylation by DNA Strand Breaks.

Wenjia Kang, Abu Hamza, Alyson M Curry, Evan Korade, Dickson Donu, Yana Cen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Facile Synthesis of H-L-Photo-Lysine and Its Genetic Incorporation Into Proteins.Chembiochem : a European journal of chemical biology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wenjia KangDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298-0540, United States.
Abu HamzaDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298-0540, United States.
Alyson M CurryDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298-0540, United States.
Evan KoradeDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298-0540, United States.
Dickson DonuDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298-0540, United States.
Yana CenDepartment of Medicinal Chemistry, Virginia Commonwealth University, Richmond, Virginia 23298-0540, United States.ORCID https://orcid.org/0000-0001-6436-5744
Virginia Commonwealth University · US

Funding

Vermont INBRE Administrative Supplement 2024 AWD 118P20GM103449 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI CHRISTOPHER S FRANCKLYN · 2012 to 2026
$58.4M
NIGMS NIH HHS P20 GM103449
6 · The paper itself

Abstract

SIRT6 is an emerging regulator of longevity. Overexpression of SIRT6 extends the lifespan of mice. Conversely, SIRT6 knockout mice demonstrate severe metabolic defects and a shortened lifespan. The discrepancy between SIRT6's weak

Identifiers

PMID37970049
PMCPMC10633859
OpenAlexW4387872052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.