Evidence map›Paper›PMID 37970015›Full record

ArticleACS omega2023

Noncovalent Interaction of Lactoferrin with Epicatechin and Epigallocatechin: Focus on Fluorescence Quenching and Antioxidant Properties.

Junliang Chen, Shuhua Ma, Xin Chen, Xin Dai, Li Zhang, Yunxia Yuan, Linlin Li, Hui Zhang, Gangtian Liu, Guangyue Ren and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Junliang ChenCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Shuhua MaCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Xin ChenCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Xin DaiCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Li ZhangCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Yunxia YuanCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Linlin LiCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Hui ZhangCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Gangtian LiuCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Guangyue RenCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Xu DuanCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.
Qinggang XieHeilongjiang Feihe Dairy Co., Ltd., Beijing 100015, China.
Weiwei CaoCollege of Food and Bioengineering, Henan University of Science and Technology, Luoyang, Henan 471023, China.ORCID https://orcid.org/0000-0001-8383-9933
Henan University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lactoferrin (LF) from bovine milk possesses antioxidant activity, immune regulatory and other biological activities. However, the effects of epicatechin (EC) and epigallocatechin (EGC) interacting with LF on the antioxidant activity of LF have not been investigated. Therefore, this study aimed to explore their interaction mechanism and the antioxidant activity of LF. UV spectra revealed that EGC (100 μM) induced a higher blue shift of LF at the maximum absorption wavelength than that of EC (100 μM). Fluorescence spectra results suggested that LF fluorescence was quenched by EC and EGC in the static type, which changed the polarity of the microenvironment around LF. The quenching constants

Identifiers

PMID37970015
PMCPMC10633880
OpenAlexW4388268761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.