Evidence map›Paper›PMID 37969836›Full record

ArticleJournal of gastrointestinal oncology2023

Latin American young patients with gastric adenocarcinoma: worst prognosis and outcomes.

Germán Calderillo-Ruíz, María Consuelo Díaz-Romero, Berenice Carbajal-López, Marytere Herrera-Martínez, Erika Ruiz-García, Alberto M Leon-Takahashi, Horacio Noé López-Basave, Abelardo Meneses-García, Ángel Herrera-Gomez

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Article in Journal of gastrointestinal oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Comprehensive histopathological analysis of gastric cancer in European and Latin America populations reveals differences in PDL1, HER2, p53 and MUC6 expression.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Germán Calderillo-RuízGastrointestinal Functional Unit, National Cancer Institute, Mexico City, Mexico.
María Consuelo Díaz-RomeroGastrointestinal Functional Unit, National Cancer Institute, Mexico City, Mexico.
Berenice Carbajal-LópezClinical Research Department-Gastrointestinal Functional, National Cancer Institute, Mexico City, Mexico.
Marytere Herrera-MartínezGastrointestinal Functional Unit, National Cancer Institute, Mexico City, Mexico.
Erika Ruiz-GarcíaGastrointestinal Functional Unit, National Cancer Institute, Mexico City, Mexico.
Alberto M Leon-TakahashiGastrointestinal Functional Unit, National Cancer Institute, Mexico City, Mexico.
Horacio Noé López-BasaveGastrointestinal Functional Unit, National Cancer Institute, Mexico City, Mexico.
Abelardo Meneses-GarcíaDivision of Pathology, National Cancer Institute, Mexico City, Mexico.
Ángel Herrera-GomezDivision of Surgical Oncology, National Cancer Institute, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Incidence of young patients (aged 40 years or younger) diagnosed with gastric carcinoma has increased worldwide. Young GC diagnosis, have clinicopathological features that differ from elderly, and is correlated with bad prognosis factors. The purpose of this work is to describe the prevalence, clinic-pathological features, and prognosis of overall survival (OS) of young Latin-American patients with GC. Methods: Retrospective, observational study. Included patients treated at the National Cancer Institute [2004-2020]. Statistical analysis: χ Results: A total of 2,543 patients fulfilled the inclusion criteria. Young-patients were predominantly female (54%), with diffuse-type adenocarcinoma (68%), signet-ring-cell (72%), poor-differentiation (90%), and metastatic (79%). In OS analysis, patients with metastatic disease, showed differences regarding age, young patients reported a median-OS of 8 versus 13 months for elderly patients (P=0.001). Among young patients, differences were also observed regarding gender, young-female patients had a median-OS of 5 versus 11 months for young-man (P=0.001). Conclusions: This is one of the pioneer studies correlating age with gender and the prognostic features of bad prognosis in Latin-American population. Besides, supports the idea that a global effort is required to improve awareness, prevention, and early diagnosis of GC.

Indexed as

female patientsGastric adenocarcinomaoverall survival (OS)prognostic factorsyoung population

Identifiers

PMID37969836
PMCPMC10643594

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.