Evidence map›Paper›PMID 37969808›Full record

ArticleJournal of advanced veterinary and animal research2023

Humoral immune responses in different stages of wound healing in Black Bengal goats.

Kanika Samaddar, Mohammad Habibur Rahman, Md Leonur Islam Leon, Md Sohel Rana, Md Mehedi Hasan, Ziaul Haque, Md Mizanur Rahman

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced veterinary and animal research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kanika SamaddarDepartment of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Mohammad Habibur RahmanImmunology and Vaccinology Laboratory, Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Leonur Islam LeonImmunology and Vaccinology Laboratory, Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Sohel RanaImmunology and Vaccinology Laboratory, Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Mehedi HasanImmunology and Vaccinology Laboratory, Department of Microbiology and Hygiene, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Ziaul HaqueDepartment of Anatomy and Histology, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Md Mizanur RahmanDepartment of Surgery and Obstetrics, Bangladesh Agricultural University, Mymensingh, Bangladesh.
Bangladesh Agricultural University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The current study was carried out to assess the humoral immune responses according to age at different stages of wound healing in Black Bengal goats (BBG). Materials and Methods: Apparently, healthy BBGs ( Results: The normal range of immune cells in control BBGs was immunoglobulin G (IgG) (20.21 ± 0.13 mg/ml), immunoglobulin M (IgM) (2.87 ± 0.0.05 mg/ml), immunoglobulin A (IgA) (0.33 ± 0.01 mg/ml), and IL-6 (1.6 ± 0.05 pg/ml). In this experiment, higher concentrations of IgG (21.11 ± 0.20 mg/ml), IgM (2.92 ± 0.04 mg/ml), IgA (0.35 ± 0.02 mg/ml), and IL-6 (1.62 ± 0.05 pg/ml) were found in Group B BBGs, whereas the lower levels of IgG, IgM, IgA, and IL-6 were found at 17.16 ± 0.18 mg/ml, 2.12 ± 0.01 mg/ml, 0.29 ± 0.03 mg/ml, and 1.55 ± 0.05 pg/ml, respectively, in the Group E BBGs. Rapid wound healing was observed in the older groups compared to the younger groups of BBGs. The concentrations of Igs (IgG, IgM, and IgA) and IL-6 were gradually increased in all groups from day 3 (early inflammatory stage) and day 7 (late inflammatory stage), and then they decreased gradually from day 14 (proliferative stage) to reach the final stage of day 21 (remodeling stage), where the concentrations were found to be at a level comparable to their per-incisional period. No gender-related differences were detected. Conclusion: Adult BBGs (3 to 5 years old) showed faster wound repair and stronger immune responses. This finding may assist veterinarians and researchers in considering age-related immune responses for the recovery and rapid cure of surgical wounds.

Indexed as

black Bengal goatELISAHumoral immune responsesIgsIL-6wound healing

Identifiers

PMID37969808
PMCPMC10636075
OpenAlexW4387915502

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