Evidence map›Paper›PMID 37969678›Full record

ArticleSouth Asian journal of cancer2023

Rare Case of Extracranial Metastases in a Patient with IDH-Mutant Glioblastoma.

Rishan Thimma Sudarsan, Vishnu Ramanujan, Adhithyan Rajendran, Sadiya Shafi, Sushma Patil, Siddhartha Ghosh, Rakesh Jalali

Open access · diamondAbstract readCase Reports
In one paragraph

Article in South Asian journal of cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rishan Thimma SudarsanDepartment of Radiation Oncology, Neuro-Oncology Cancer Management Team, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India.
Vishnu RamanujanDepartment of Orthopedic Oncology, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India.
Adhithyan RajendranDepartment of NeuroRadiology, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India.
Sadiya ShafiDepartment of NeuroPathology, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India.ORCID 0000-0003-4674-2280
Sushma PatilDepartment of NeuroPathology, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India.
Siddhartha GhoshDepartment of Neurosurgery, Apollo Hospitals, Chennai, Tamil Nadu, India.
Rakesh JalaliDepartment of Radiation Oncology, Neuro-Oncology Cancer Management Team, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India.
Apollo Proton Cancer Centre · INApollo Hospitals · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rishan Thimma SudarsanGlioblastoma are known for its aggressive intracranial course of disease, where the overall survival is less than 18 months. Of late, the World Health Organization has reclassified and renamed secondary glioblastomas as isocitrate dehydrogenase (IDH)-mutant grade 4 astrocytomas, which is relatively better than its IDH wild-type counterpart; however, overall survival remains poor. In such tumors, metastases outside the craniospinal neuraxis is very rare, and does sometimes present with symptoms which create a diagnostic dilemma and arriving at such diagnosis is still challenging even for the best of the clinicians worldwide. Here we present such a rare case scenario, where a grade 4 astrocytoma that has transformed from a low-grade glioma, presenting with bone metastases, its workup, treatment, and various possible mechanisms underlying such a rare event, and the need of such clinical scenario especially long-term survivors to be wary of distant metastases.

Indexed as

astrocytomaextracranialglioblastomaIDHmetastases

Identifiers

PMID37969678
PMCPMC10635773
OpenAlexW4313477839

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.