Thomas P Corner, Ryan Z R Teo, Yue Wu, Eidarus Salah, Yu Nakashima, Giorgia Fiorini, Anthony Tumber, Amelia Brasnett, James P Holt-Martyn, William D Figg and 3 more
Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
13 authors at 3 institutions in 3 countries.
Thomas P CornerChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.ORCID https://orcid.org/0000-0002-6419-2094
Ryan Z R TeoChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.ORCID https://orcid.org/0000-0001-5877-2773
Yue WuState Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Design and Optimization and Department of Chemistry, China Pharmaceutical University Nanjing 211198 China zxj@cpu.edu.cn.
Eidarus SalahChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.
Giorgia FioriniChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.
Anthony TumberChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.
Amelia BrasnettChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.
James P Holt-MartynChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.
William D FiggChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.
Xiaojin ZhangState Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Design and Optimization and Department of Chemistry, China Pharmaceutical University Nanjing 211198 China zxj@cpu.edu.cn.ORCID https://orcid.org/0000-0002-1898-3071
Lennart BrewitzChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.ORCID https://orcid.org/0000-0002-9465-777X
Christopher J SchofieldChemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road OX1 3TA Oxford United Kingdom lennart.brewitz@chem.ox.ac.uk christopher.schofield@chem.ox.ac.uk.ORCID https://orcid.org/0000-0002-0290-6565
University of Oxford · GBChina Pharmaceutical University · CNUniversity of Toyama · JP
Funding
Cancer Research UK TICCPP-2022/100001Wellcome Trust
6 · The paper itself
Abstract
The human 2-oxoglutarate (2OG)- and Fe(ii)-dependent oxygenases factor inhibiting hypoxia-inducible factor-α (FIH) and HIF-α prolyl residue hydroxylases 1-3 (PHD1-3) regulate the response to hypoxia in humans
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Structure-guided optimisation of · full record | OpenQuestion