Evidence map›Paper›PMID 37969588›Full record

ArticleChemical science2023

Illuminating milling mechanochemistry by tandem real-time fluorescence emission and Raman spectroscopy monitoring.

Patrick A Julien, Mihails Arhangelskis, Luzia S Germann, Martin Etter, Robert E Dinnebier, Andrew J Morris, Tomislav Friščić

Abstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Frontiers in chemistry · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Patrick A JulienDepartment of Chemistry, McGill University 801 Sherbrooke St. W. H3A 0B8 Montreal Canada tomislav.friscic@mcgill.ca.ORCID https://orcid.org/0000-0002-7032-1198
Mihails ArhangelskisDepartment of Chemistry, McGill University 801 Sherbrooke St. W. H3A 0B8 Montreal Canada tomislav.friscic@mcgill.ca.ORCID https://orcid.org/0000-0003-1150-3108
Luzia S GermannDepartment of Chemistry, McGill University 801 Sherbrooke St. W. H3A 0B8 Montreal Canada tomislav.friscic@mcgill.ca.ORCID https://orcid.org/0000-0003-1760-5842
Martin EtterDeutsches-Elektronen Synchrotron (DESY) Notkestrasse 85 22607 Hamburg Germany.ORCID https://orcid.org/0000-0002-5183-3585
Robert E DinnebierMax-Planck Institute for Solid State Research Heisenbergstrasse 1 D-70569 Stuttgart Germany.ORCID https://orcid.org/0000-0003-2778-2113
Andrew J MorrisSchool of Metallurgy and Materials, University of Birmingham Birmingham B15 2TT UK a.j.morris.1@bham.ac.uk.ORCID https://orcid.org/0000-0001-7453-5698
Tomislav FriščićDepartment of Chemistry, McGill University 801 Sherbrooke St. W. H3A 0B8 Montreal Canada tomislav.friscic@mcgill.ca.ORCID https://orcid.org/0000-0002-3921-7915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In pursuit of accessible and interpretable methods for direct and real-time observation of mechanochemical reactions, we demonstrate a tandem spectroscopic method for monitoring of ball-milling transformations combining fluorescence emission and Raman spectroscopy, accompanied by high-level molecular and periodic density-functional theory (DFT) calculations, including periodic time-dependent (TD-DFT) modelling of solid-state fluorescence spectra. This proof-of-principle report presents this readily accessible dual-spectroscopy technique as capable of observing changes to the supramolecular structure of the model pharmaceutical system indometacin during mechanochemical polymorph transformation and cocrystallisation. The observed time-resolved

Identifiers

PMID37969588
PMCPMC10631231

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.