Evidence map›Paper›PMID 37969303›Full record

ArticleJournal of thoracic disease2023

Osimertinib as first-line treatment for recurrent lung cancer patients with

Atsushi Osoegawa, Takashi Karashima, Yohei Takumi, Takahiro Sato, Miyuki Abe, Takafumi Hashimoto, Kenji Sugio

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Circular RNAJournal of thoracic disease · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Atsushi OsoegawaDepartment of Thoracic and Breast Surgery, Oita University Faculty of Medicine, Yufu, Japan.
Takashi KarashimaDepartment of Thoracic and Breast Surgery, Oita University Faculty of Medicine, Yufu, Japan.
Yohei TakumiDepartment of Thoracic and Breast Surgery, Oita University Faculty of Medicine, Yufu, Japan.
Takahiro SatoDepartment of Thoracic and Breast Surgery, Oita University Faculty of Medicine, Yufu, Japan.
Miyuki AbeDepartment of Thoracic and Breast Surgery, Oita University Faculty of Medicine, Yufu, Japan.
Takafumi HashimotoDepartment of Thoracic and Breast Surgery, Oita University Faculty of Medicine, Yufu, Japan.
Kenji SugioDepartment of Thoracic and Breast Surgery, Oita University Faculty of Medicine, Yufu, Japan.
Oita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although osimertinib was approved as adjuvant therapy for lung cancer patients with Methods: Patients who received osimertinib as first-line treatment for postoperative recurrence between September 2018 and January 2023 were included. Clinicopathological factors, duration of osimertinib treatment (DoT), and adverse events were collected and analyzed. Results: Twenty patients received osimertinib [male, n=6; median age, 75 years (range, 55-85 years)]. The Conclusions: Although osimertinib exerts great disease control, even in patients with brain metastasis or poor PS, their presence was associated with a poor prognosis, even with osimertinib treatment. Therefore, adjuvant osimertinib is recommended unless contraindicated.

Indexed as

Adjuvant therapycase seriesmolecular targeting therapyosimertinibrelapsed resected non-small cell lung cancer (relapsed resected NSCLC)

Identifiers

PMID37969303
PMCPMC10636461
OpenAlexW4388102737

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.