Evidence map›Paper›PMID 37969197›Full record

ArticleAmerican journal of translational research2023

Attenuating effects of

Abubakar Awwal Yusuf, Bashir Lawal, Uchenna Blessing Alozieuwa, Amos S Onikanni, Halimat Yusuf Lukman, Adewale O Fadaka, Femi Olawale, Obinna Osuji, Saidu Sani, Mayowa Solomon Owolabi and 5 more

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 69% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Investigating the Antidiabetic Effects ofFood science & nutrition · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 7 countries.

Abubakar Awwal YusufDepartment of Biochemistry, IBB University Lapai, Nigeria.
Bashir LawalPhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Academia Sinica Taipei 11529, Taiwan.
Uchenna Blessing AlozieuwaDepartment of Biochemistry, Veritas University Abuja Bwari, FCT-Abuja, Nigeria.
Amos S OnikanniGraduate Institute of Biomedical Sciences, College of Medicine, China Medical University Taichung, Taiwan.
Halimat Yusuf LukmanDepartment of Chemical Sciences, Biochemistry Unit, College of Natural and Applied Sciences, Summit University Offa, PMB 4412, Nigeria.
Adewale O FadakaDepartment of Biotechnology, University of The Western Cape Belleville, South Africa.
Femi OlawaleNano Gene and Drug Delivery Group, University of Kwazulu Natal South Africa.
Obinna OsujiDepartment of Chemistry, Faculty of Physical Sciences, Alex Ekwueme Federal University Ndufu Alike P.M.B 1010, Abakaliki, Ebonyi State, Nigeria.
Saidu SaniDepartment of Biochemistry and Molecular Biology, Faculty of Science, Federal University Ndufu-Alike Ikwo P.M.B. 1010, Abakaliki, Ebonyi State, Nigeria.
Mayowa Solomon OwolabiDepartment of Breast Cancer, Baylor College of Medicine USA.
Abdulsalam H AdewuyiDepartment of Biochemistry, Federal University of Technology Minna Nigeria.
Deborah H YusufDepartment of Biochemistry, IBB University Lapai, Nigeria.
Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University Damanhour 22511, AlBeheira, Egypt.
Farid S AtayaDepartment of Biochemistry, College of Science, King Saud University PO Box 2455, Riyadh 11451, Saudi Arabia.
Dalia FouadDepartment of Zoology, College of Science, King Saud University PO Box 22452, Riyadh 11495, Saudi Arabia.
Funai Electric (Japan) · JPIbrahim Badamasi Babangida University · NGKing Saud University · SABaylor College of Medicine · USChina Medical University · TWDamanhour University · EGFederal University of Technology Minna · NGTaipei Medical University · TWUniversity of KwaZulu-Natal · ZAUniversity of Nigeria · NGUniversity of the Western Cape · ZAVeritas University · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe use of medicinal plants for diabetes treatment is increasing owing to their effectiveness and safety compared to synthetic drugs. Thus, the ameliorative effects of

methodsRats with alloxan (120 mg/kg body weight (BW))-induced diabetes were randomized into different groups (

resultsOur data revealed that treatment with the crude extract caused a dose-dependent hypoglycemic effect of 61.32±3.45%, 76.05±3.05%, and 78.59±5.90% at 100, 200, and 400 mg/kg BW, respectively and improved the BW of the animals. The extract also ameliorated the elevated cholesterol, triglyceride, low-density lipoprotein cholesterol, and increased serum levels of high-density lipoprotein cholesterol compared with untreated control animals. The extract also reversed serum biochemical alterations in aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, creatinine, total and direct bilirubin, urea, and uric acid that were observed in untreated diabetic rats. Interestingly, the

conclusionCollectively, this study suggests the potential application of

Indexed as

Azanza garckeanabiochemical parametersdyslipidemiahepatopathynephropathy

Identifiers

PMID37969197
PMCPMC10641334
OpenAlexW4388737378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.