Evidence map›Paper›PMID 37968705›Full record

ReviewJournal of nanobiotechnology2023

Size and charge effects of metal nanoclusters on antibacterial mechanisms.

Hanny Tika Draviana, Istikhori Fitriannisa, Muhamad Khafid, Dyah Ika Krisnawati, Widodo, Chien-Hung Lai, Yu-Jui Fan, Tsung-Rong Kuo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 99 citations in OpenAlex.

  1. Virulence · 2026
    Review
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  11. Phase-Dependent MoSInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hanny Tika Draviana *Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.
Istikhori Fitriannisa *Graduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.
Muhamad KhafidDepartment of Nursing, Faculty of Nursing and Midwivery, Universitas Nahdlatul Ulama Surabaya, Surabaya, 60237, East Java, Indonesia.
Dyah Ika KrisnawatiDharma Husada Nursing Academy, Kediri, 64117, East Java, Indonesia.
WidodoSekolah Tinggi Teknologi Pomosda, Nganjuk, 64483, East Java, Indonesia.
Chien-Hung LaiDepartment of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 11031, Taiwan. chlai@tmu.edu.tw.
Yu-Jui FanInternational PhD Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan. ray.yj.fan@tmu.edu.tw.
Tsung-Rong KuoGraduate Institute of Nanomedicine and Medical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan. trkuo@tmu.edu.tw.
Taipei Medical University · TWInstitut Sains dan Teknologi Terpadu Surabaya · IDUniversitas Nahdlatul Ulama SurabayaUniversity of Surabaya · ID

Funding

National Science and Technology Council NSTC 112-2113-M-038-005
6 · The paper itself

Abstract

Nanomaterials, specifically metal nanoclusters (NCs), are gaining attention as a promising class of antibacterial agents. Metal NCs exhibit antibacterial properties due to their ultrasmall size, extensive surface area, and well-controlled surface ligands. The antibacterial mechanisms of metal NCs are influenced by two primary factors: size and surface charge. In this review, we summarize the impacts of size and surface charge of metal NCs on the antibacterial mechanisms, their interactions with bacteria, and the factors that influence their antibacterial effects against both gram-negative and gram-positive bacteria. Additionally, we highlight the mechanisms that occur when NCs are negatively or positively charged, and provide examples of their applications as antibacterial agents. A better understanding of relationships between antibacterial activity and the properties of metal NCs will aid in the design and synthesis of nanomaterials for the development of effective antibacterial agents against bacterial infections. Based on the remarkable achievements in the design of metal NCs, this review also presents conclusions on current challenges and future perspectives of metal NCs for both fundamental investigations and practical antibacterial applications.

Indexed as

Metal NanoparticlesAnti-Bacterial AgentsGoldAnti-Bacterial AgentsGoldAntibacterial mechanismLigandMetal nanoclustersNanomaterialsSizeSurface charge

Identifiers

PMID37968705
PMCPMC10648733
OpenAlexW4388698713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.