Evidence map›Paper›PMID 37968692›Full record

ReviewJournal of intensive care2023

Translation of patients' advance directives in intensive care units: are we there yet?

Sira M Baumann, Natalie J Kruse, Paulina S C Kliem, Simon A Amacher, Sabina Hunziker, Tolga D Dittrich, Fabienne Renetseder, Pascale Grzonka, Raoul Sutter

Abstract readReview
In one paragraph

Review in Journal of intensive care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Advance care planning in patients with respiratory failure.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sira M Baumann *Intensive Care Unit, Department of Acute Medical Care, University Hospital Basel, Basel, Switzerland.
Natalie J Kruse *Intensive Care Unit, Department of Acute Medical Care, University Hospital Basel, Basel, Switzerland.
Paulina S C KliemIntensive Care Unit, Department of Acute Medical Care, University Hospital Basel, Basel, Switzerland.
Simon A AmacherIntensive Care Unit, Department of Acute Medical Care, University Hospital Basel, Basel, Switzerland.
Sabina HunzikerDepartment of Clinical Research, University of Basel, Basel, Switzerland.
Tolga D DittrichDepartment of Clinical Research, University of Basel, Basel, Switzerland.
Fabienne RenetsederIntensive Care Unit, Department of Acute Medical Care, University Hospital Basel, Basel, Switzerland.
Pascale GrzonkaIntensive Care Unit, Department of Acute Medical Care, University Hospital Basel, Basel, Switzerland.
Raoul SutterIntensive Care Unit, Department of Acute Medical Care, University Hospital Basel, Basel, Switzerland. raoul.sutter@usb.ch.ORCID http://orcid.org/0000-0002-6575-356X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis review examined studies regarding the implementation and translation of patients' advance directives (AD) in intensive care units (ICUs), focusing on practical difficulties and obstacles.

methodsThe digital PubMed and Medline databases were screened using predefined keywords to identify relevant prospective and retrospective studies published until 2022.

resultsSeventeen studies from the United States, Europe, and South Africa (including 149,413 patients and 1210 healthcare professionals) were identified. The highest prevalence of ADs was described in a prospective study in North America (49%), followed by Central Europe (13%), Asia (4%), Australia and New Zealand (4%), Latin America (3%), and Northern and Southern Europe (2.6%). While four retrospective studies reported limited effects of ADs, four retrospective studies, one survey and one systematic review indicated significant effects on provision of intensive care, higher rates of do-not-resuscitate orders, and care withholding in patients with ADs. Four of these studies showed shorter ICU stays, and lower treatment costs in patients with ADs. One prospective and two retrospective studies reported issues with loss, delayed or no transmission of ADs. One survey revealed that 91% of healthcare workers did not regularly check for ADs. Two retrospective studies and two survey revealed that the implementation of directives is further challenged by issues with their applicability, phrasing, and compliance by the critical care team and family members.

conclusionsAlthough ADs may improve intensive- and end-of-life care, insufficient knowledge, lack of awareness, poor communication between healthcare providers and patients or surrogates, lack of standardization of directives, as well as ethical and legal concerns challenge their implementation.

Indexed as

Advance directivesIntensive careNeurocritical illnessPatients’ will

Identifiers

PMID37968692
PMCPMC10648602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.