ArticleJournal of orthopaedic surgery and research2023
Role of Charlson comorbidity index in predicting the ICU admission in patients with thoracic aortic aneurysm undergoing surgery.
Article in Journal of orthopaedic surgery and research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Shifting Trends in Intensive Cardiovascular Care Unit Admission Patterns: Retrospective Insights and Prospective Implications.Diagnostics (Basel, Switzerland) · 2025Article
- Evaluation of ASA, SORT, and ACCI Scores in Predicting the Need for Postoperative Intensive Care Unit Admissions After Hip Surgery.Turkish journal of anaesthesiology and reanimation · 2025Article
- Systemic Inflammation Index (SII) as a Predictor of Mortality in Intensive Care Units.Biomedicines · 2025Article
- Development and Validation of a Risk Score for Predicting ICU Admission in Adults with New-Onset Encephalitis.Neurocritical care · 2025Article
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Authors and funding
7 authors.
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Abstract
objectivesThis study aimed to explore the value of the Charlson comorbidity index (CCI) in predicting ICU admission in patients with aortic aneurysm (AA).
methodsThe clinical data of patients were obtained from the Medical Information Mart for Intensive Care-IV database. The association between CCI and ICU admission was explored by restricted cubic spline (RCS), threshold effect analysis, generalized linear model, logistic regression, interaction, and mediation analyses. Its clinical value was evaluated by decision curve analysis (DCA), receiver operating characteristic curve (ROC), DeLong's test, and net reclassification index (NRI) analyses.
resultsThe ICU admission was significantly associated with the thoracic AA (TAA), unruptured status, and surgery status. Therefore, 288 candidate patients with unruptured TAA who received surgery were enrolled in the further analysis. We found that CCI was independently associated with the ICU admission of candidates (P = 0.005). Further, their nonlinear relationship was observed (adjusted P = 0.008), and a significant turning point of 6 was identified. The CCI had a favorable performance in predicting ICU admission (area under curve = 0.728) and achieved a better clinical net benefit. New models based on CCI significantly improved the accuracy of prediction. Besides the importance of CCI in ICU admission, CCI also exerted important interaction effect (rather than mediating effects) on the association of other variables (such as age and blood variables) with ICU admission requirements (all P < 0.05).
conclusionsThe CCI is an important predictor of ICU admission after surgery in patients with unruptured TAA.
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