ArticleBMC geriatrics2023
Association between frailty and chronic constipation and chronic diarrhea among American older adults: National Health and Nutrition Examination Survey.
Article in BMC geriatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 26 citations in OpenAlex.
- Colon Capsule Endoscopy-Measured Colonic Transit Time Is Associated with Frailty in Older Adults.Medicina (Kaunas, Lithuania) · 2026Article
- The impact of frailty scores on latent tuberculosis infection and all-cause mortality in this population.Medicine · 2026Article
- Validation of the Turkish Version of Rapid Geriatric Assessment in Hospitalized Older Adults: A Preliminary Study.Florence Nightingale journal of nursing · 2025Article
- Review
- Association between the Zhejiang University index and chronic diarrhea: a cross-sectional study.European journal of medical research · 2025Article
- Dose-Dependent Effects of Dietary n-3 Fatty Acids on Bowel Health: Plant-Sourced ALA Modulates Diarrhea Risk While Marine-Sourced DHA/EPA Prevent Constipation in NHANES 2005-2010.Food science & nutrition · 2025Article
- Relationship of the oxidative balance score with the risk of frailty and mortality in patients with asthma: a mediation analysis of NHANES.BMC pulmonary medicine · 2025Article
- The Prognostic Role of Serum Procalcitonin for Adult Patients with Acute Diarrhea in the Emergency Department.Diagnostics (Basel, Switzerland) · 2025Article
- Dietary intake of live microbes and its association with frailty in older adults: a NHANES analysis (1999-2018).BMC geriatrics · 2025Article
- Association of the body roundness index with chronic diarrhea and chronic constipation: findings based on the National Health and Nutrition Examination Survey 2005-2010 data.Lipids in health and disease · 2025Article
- Analysis of alterations in the composition of the intestinal microbiota in frail older individuals.PloS one · 2025Article
- Associations Between Complement C4, Habitual Constipation, and Sleep Disturbance in Oldest-Old and Centenarian Chinese Adults.Journal of inflammation research · 2025Article
- Inflammatory parameters mediates the relationship between dietary index for gut microbiota and frailty in middle-aged and older adults in the United States: findings from a large-scale population-based study.Frontiers in nutrition · 2025Article
- Cross-sectional association between hs-CRP/HDL-C ratio and physical frailty among middle-aged and older adults: findings from a population-based study.Frontiers in public health · 2025Article
- Joint association of frailty and depression with new-onset digestive disease among elderly Chinese population.Frontiers in nutrition · 2025Article
- Volatile organic compounds exposure associated with frailty in United States adults from NHANES 2011-2018.Frontiers in public health · 2025Article
- Dietary inflammation and socioeconomic status mediate depression-constipation link: a cross-sectional analysis of NHANES 2005-2010.Frontiers in nutrition · 2025Article
- Acute Diarrhea in a Tertiary Emergency Department: From Readmission Determinants to Antibiotic Prescription.Antibiotics (Basel, Switzerland) · 2024Article
- Diminished representation of vitamin-B12-producing bacteria in constipated elders with frailty.iScience · 2024Article
- Association between cardiometabolic index and frailty among patients with diabetes mellitus: a cross-sectional study.Frontiers in nutrition · 2024Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThis study was to explore the relationship between chronic constipation, chronic diarrhea, and frailty in older Americans.
methodsThis cross-sectional study selected a total of 4241 community-dwelling individuals aged 60 years and older from the 2005-2010 National Health and Nutrition Examination Survey. Frailty was measured using a 49-item frailty index, and a frailty index > 0.21 was defined as a frail status. Chronic constipation and chronic diarrhea were defined as the "usual or most common type of stool" by the Bristol Stool Form Scale (BSFS) Types 1 and 2 and BSFS Types 6 and 7, respectively. Weighted logistic regression analysis was used to examine the relationship between gut health and frailty status. Restricted cubic spline (RCS) curves were built to assess the association between frailty index and stool frequency.
resultsFrailty status was associated with higher odds of constipation in an unadjusted model; however, after further adjusting for confounding variables, the relationship between frailty status and constipation was not statistically significant. We discovered a positive correlation between the frailty status and diarrhea after adjustment for all variables. The frailty index showed a U-shaped relationship with stool frequency, and the frailty index was the smallest at a frequency of 10 stools/week.
conclusionNegative associations were observed between frailty status and chronic constipation and diarrhea among older adults. Older adults who have a bowel movement frequency of about 10 times per week are the least frail. Future studies are warranted to confirm the causal relationship in this association.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.