Evidence map›Paper›PMID 37968538›Full record

ArticlePediatric nephrology (Berlin, Germany)2024

Kidney function and transplants in prune belly syndrome: a scoping review.

Adree Khondker, Ihtisham Ahmad, Kellie Kim, Shamir Malik, Jin K Kim, Michael Chua, Juliane Richter, Justin Yh Chan, Linda A Baker, Armando J Lorenzo and 1 more

Abstract readScoping Review
PubMed Publisher
In one paragraph

Article in Pediatric nephrology (Berlin, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Adree KhondkerTemerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Ihtisham AhmadTemerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Kellie KimTemerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Shamir MalikTemerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Jin K KimDivision of Urology, Department of Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Michael ChuaDivision of Urology, Department of Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Juliane RichterDivision of Urology, Department of Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Justin Yh ChanDivision of Urology, Department of Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Linda A BakerDivision of Pediatric Urology, Department of Surgery, Nationwide Children's Hospital, Columbus, OH, USA.
Armando J LorenzoDivision of Urology, Department of Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Mandy RickardDivision of Urology, Department of Surgery, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada. mandy.rickard@sickkids.ca.ORCID 0000-0003-0598-1824
University of Toronto · CAHospital for Sick Children · CANationwide Children's Hospital · US

Funding

Prune Belly SyndromeR01DK105068 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI BAKER, LINDA A. · 2015 to 2019
$1.8M
NIDDK NIH HHS R01 DK105068
6 · The paper itself

Abstract

backgroundChildren with prune belly syndrome (PBS) are at higher risk of developing kidney dysfunction and requiring kidney replacement therapy (KRT). While studies have described surgical and survival outcomes in these populations, there has yet to be a focused synthesis of evidence regarding kidney outcomes in this population. Here, the focus of this scoping review was to highlight knowledge gaps and report standards on kidney outcomes in PBS of all ages.

methodsFollowing scoping review methodology, EMBASE, MEDLINE, and Scopus were searched for peer-reviewed literature that describe kidney outcomes in PBS. All studies with a broad set of kidney outcomes (such as kidney function measures, chronic kidney disease (CKD), KRT and associated outcomes) were included. Findings were summarized and qualitatively synthesized.

resultsOf the 436 unique records identified, 25 were included for synthesis. A total of 17 studies (441 patients) reported on kidney insufficiency outcomes, with an estimated prevalence of CKD ranging from 8 to 66%. A total of 15 studies (314 patients) described KRT, primary kidney transplant, and outcomes. Of these, the age for KRT ranged from 4 to 21 years, and graft survival ranged from 22 to 87% by last follow-up (range 1.3-27 years).

conclusionsThere is significant variability in studies reporting kidney outcomes in PBS which limits meaningful synthesis. There is a need for future studies with comprehensive reporting of confounders and drivers for kidney insufficiency in PBS.

Indexed as

Kidney TransplantationPrune Belly SyndromeRenal Insufficiency, ChronicAdolescentAdultChildChild, PreschoolHumansKidneyRenal Replacement TherapyYoung AdultKidney insufficiencyKidney transplantPrune belly syndrome

Identifiers

PMID37968538
OpenAlexW4388712364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.